Pharmaceutical Information |
Drug Name |
Bedaquiline fumarate |
Drug ID |
BADD_D00222 |
Description |
Bedaquiline is a bactericidal antimycobacterial drug. Chemically it is a diarylquinoline. FDA approved on December 28, 2012. |
Indications and Usage |
Bedaquiline is indicated as part of combination therapy in adults (≥ 18 years) with pulmonary multi-drug resistant tuberculosis (MDR-TB). |
Marketing Status |
Prescription |
ATC Code |
J04AK05 |
DrugBank ID |
DB08903
|
KEGG ID |
D09873
|
MeSH ID |
C493870
|
PubChem ID |
24812732
|
TTD Drug ID |
D0Y4QG
|
NDC Product Code |
59676-702; 59676-701; 69766-058 |
Synonyms |
bedaquiline | (1R,2S)-1-(6-bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-(3-fluorophenyl)-1-phenyl-butan-2-ol | R207910 | TMC207 | AIDS222088 | AIDS-222089 | bedaquiline fumarate |
|
Chemical Information |
Molecular Formula |
C36H35BrN2O6 |
CAS Registry Number |
845533-86-0 |
SMILES |
CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O.C(=CC(
=O)O)C(=O)O |
Chemical Structure |
|
|
ADR Related Proteins Induced by Drug |
ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
Not Available | Not Available | Not Available | Not Available | Not Available |
|
ADRs Induced by Drug |
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