| Pharmaceutical Information |
| Drug Name |
Bedaquiline |
| Drug ID |
BADD_D00221 |
| Description |
Bedaquiline is a bactericidal antimycobacterial drug. Chemically it is a diarylquinoline. FDA approved on December 28, 2012. |
| Indications and Usage |
Bedaquiline is indicated as part of combination therapy in adults (≥ 18 years) with pulmonary multi-drug resistant tuberculosis (MDR-TB). |
| Marketing Status |
Prescription |
| ATC Code |
J04AK05 |
| DrugBank ID |
DB08903
|
| KEGG ID |
D09872
|
| MeSH ID |
C493870
|
| PubChem ID |
5388906
|
| TTD Drug ID |
D0Y4QG
|
| NDC Product Code |
Not Available |
| Synonyms |
bedaquiline | (1R,2S)-1-(6-bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-(3-fluorophenyl)-1-phenyl-butan-2-ol | R207910 | TMC207 | AIDS222088 | AIDS-222089 | bedaquiline fumarate |
|
| Chemical Information |
| Molecular Formula |
C32H31BrN2O2 |
| CAS Registry Number |
843663-66-1 |
| SMILES |
CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
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