Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Barium sulfate
Drug ID BADD_D00213
Description Barium sulfate is an inorganic compound with the chemical formula BaSO4 [L1957]. Barium sulfate occurs in nature as the mineral _barite_. It is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield [L1957]. This drug is used as a contrast agent in diagnostic x-ray procedures. Therapeutic advantages of barium sulfate in diagnostic procedures include both its low water solubility and high level of clearance from the body [FDA label]. Barium sulfate is ingested by mouth or administered rectally and combined with granules of effervescent bicarbonate to enhance distension of the GI tract, allowing for enhanced gastrointestinal tract visualization [L1957], [L1959].
Indications and Usage Barium sulfate is a radiographic contrast agent indicated for use in computed tomography (CT) of the abdomen to delineate the gastrointestinal (GI) tract in adult and pediatric patients [FDA label].
Marketing Status Prescription; Discontinued
ATC Code Not Available
DrugBank ID DB11150
KEGG ID D02052
MeSH ID D001466
PubChem ID 24414
TTD Drug ID D0T5DE
NDC Product Code 32909-125; 32909-116; 32909-722; 32909-756; 32909-770; 32909-814; 32909-746; 32909-105; 32909-724; 69307-1024; 32909-741; 32909-744; 32909-187; 32909-742; 10361-778; 32909-747; 32909-927; 32909-115; 0395-0200; 32909-122; 32909-167; 32909-146; 32909-764; 32909-121; 75855-3470; 32909-750; 32909-711; 75855-3471
Synonyms Barium Sulfate | Sulfate, Barium | Micropaque Oral | Barium Sulfate (2:1) | E-Z-CAT | E Z CAT | EZCAT | Barite | Baritop
Chemical Information
Molecular Formula BaSO4
CAS Registry Number 7727-43-7
SMILES [O-]S(=O)(=O)[O-].[Ba+2]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agitation19.06.02.001; 17.02.05.012--
Asthenia08.01.01.001--Not Available
Bacteraemia11.01.11.001--
Bradycardia02.03.02.002--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Confusional state19.13.01.001; 17.02.03.005--
Cyanosis02.01.02.002; 24.03.01.007; 22.02.02.007--
Death08.04.01.001--
Diarrhoea07.02.01.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Erythema23.03.06.001--Not Available
Granuloma08.01.05.001; 23.03.15.001--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypotension24.06.03.002--
Intestinal perforation07.04.06.002--Not Available
Laryngeal oedema23.04.01.005; 22.04.02.001; 10.01.05.003--
Loss of consciousness17.02.04.004--Not Available
Nausea07.01.07.001--
Pallor24.03.04.001; 08.01.03.032; 23.03.03.031--Not Available
Peritonitis11.01.07.007; 07.19.05.004--
Pneumonia aspiration22.01.01.005--Not Available
Pneumonitis22.01.01.006--
Pruritus23.03.12.001--
Sepsis11.01.11.003--
Syncope24.06.02.012; 17.02.04.008; 02.01.02.008--
Tachycardia02.03.02.007--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Urticaria23.04.02.001; 10.01.06.001--
Vasodilatation24.03.02.003; 23.06.05.006--Not Available
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