Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Atropine sulfate
Drug ID BADD_D00190
Description An alkaloid, originally from Atropa belladonna, but found in other plants, mainly solanaceae.
Indications and Usage For the treatment of poisoning by susceptible organophosphorous nerve agents having anti-cholinesterase activity (cholinesterase inhibitors) as well as organophosphorous or carbamate insecticides.
Marketing Status Prescription; Discontinued
ATC Code A03BA01; S01FA01
DrugBank ID DB00572
KEGG ID D02069
MeSH ID D001285
PubChem ID 60196398
TTD Drug ID D0RG3O
NDC Product Code 51662-1509; 51662-1527; 0404-9823; 0404-9822; 13985-606; 52584-630; 0409-1630; 51552-1391; 0641-6006; 50268-118; 71872-7100; 70518-3120; 38779-2267; 71872-7037; 52584-002; 76329-3340; 51662-1339; 50090-4524; 51662-1311; 0404-9820; 52584-401; 63323-580; 50090-5924; 16729-512; 0409-4910; 50090-3138; 0409-4911; 16729-483; 52584-910; 0404-9821; 71872-7255; 0404-9824; 52584-029; 13371-387; 63827-1014; 71872-7002; 69205-736; 71872-7001; 71872-7245; 0517-1010; 0641-6251; 0404-9819; 16729-484; 76329-3339; 0409-9630; 16729-526; 43235-0004; 51662-1378; 51662-1289; 50090-3104; 52584-044; 51662-1207; 12714-031; 42385-736; 17478-215; 71684-0303; 70121-1705; 0517-0401; 62991-2842; 60505-6226; 62068-306; 52221-107; 55742-124; 76003-0157; 51662-1208; 71872-7246; 69205-031; 16729-525; 71872-7017; 0065-0303; 71872-7252; 24208-825; 51927-0156
Synonyms Atropine | Atropinol | Atropine Sulfate | Sulfate, Atropine | Atropine Sulfate Anhydrous | Anhydrous, Atropine Sulfate | Sulfate Anhydrous, Atropine | AtroPen | Atropin Augenöl | Augenöl, Atropin
Chemical Information
Molecular Formula C34H48N2O10S
CAS Registry Number 55-48-1
SMILES CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3.OS(= O)(=O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Atrial fibrillationNot AvailableF1PE02Not AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Leukocytosis01.02.01.002--
Local swelling08.01.03.013--Not Available
Loss of libido19.08.03.003--Not Available
Mania19.16.02.002--
Mastication disorder07.01.06.016; 17.05.03.006; 15.03.01.009--Not Available
Micturition urgency20.02.02.006--
Mucosal dryness08.01.06.001--Not Available
Mucous membrane disorder08.01.06.004--Not Available
Muscle twitching15.05.03.005--Not Available
Mydriasis17.02.11.003; 06.05.03.004--Not Available
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Nodal rhythm02.03.02.006--Not Available
Opisthotonus17.01.03.005--Not Available
Pain08.01.08.004--
Palpitations02.01.02.003--
Paranoia19.05.01.005--Not Available
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002--Not Available
Photophobia17.17.02.006; 06.01.01.004--
Photosensitivity reaction23.03.09.003--
Pleural effusion22.05.02.002--
Pulmonary oedema22.01.03.003; 02.05.02.003--
Pulse absent13.14.04.005--Not Available
Pupillary light reflex tests abnormal13.07.04.003--Not Available
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rash erythematous23.03.06.003--Not Available
Rash macular23.03.13.003--Not Available
Rash maculo-papular23.03.13.004--
Rash papular23.03.13.017--Not Available
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