Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Articaine hydrochloride
Drug ID BADD_D00170
Description Articaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Indications and Usage
Marketing Status Not Available
ATC Code N01BB08
DrugBank ID DB09009
KEGG ID D02991
MeSH ID D002355
PubChem ID 32169
TTD Drug ID D0I5HV
NDC Product Code 68108-0610; 65675-1004; 53335-0001
Synonyms Carticaine | Carticain | Articain | Articaine | Carticaine Hydrochloride | Hydrochloride, Carticaine | Hoe-40045 | Hoe 40045 | Hoe40045 | Hoe-045 | Hoe 045 | Hoe045 | Ultracaine
Chemical Information
Molecular Formula C13H21ClN2O3S
CAS Registry Number 161448-79-9
SMILES CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Blood pressure increased13.14.03.005--Not Available
Burning sensation08.01.09.029; 17.02.06.001--Not Available
Constipation07.02.02.001--
Cough22.02.03.001--
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Dry mouth07.06.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Dysmenorrhoea21.01.01.002--
Dyspepsia07.01.02.001--
Ear pain04.03.01.003--
Ecchymosis23.06.01.001; 01.01.03.001; 24.07.06.002--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Facial paralysis17.04.03.008--Not Available
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal pain07.01.05.005--
Gingival bleeding07.09.07.001; 24.07.02.010--Not Available
Gingivitis11.01.04.013; 07.09.03.003--
Glossitis07.14.01.001--Not Available
Haemoglobin13.01.05.018--Not Available
Headache17.14.01.001--
Hyperaesthesia17.02.06.004--Not Available
Hypersensitivity10.01.03.003--
Hypoaesthesia17.02.06.023--Not Available
Infection11.01.08.002--Not Available
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