Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Alteplase
Drug ID BADD_D00087
Description Human tissue plasminogen activator, purified, glycosylated, 527 residues purified from CHO cells
Indications and Usage For management of acute myocardial infarction, acute ischemic strok and for lysis of acute pulmonary emboli
Marketing Status Prescription
ATC Code B01AD02; S01XA13
DrugBank ID DB00009
KEGG ID D02837
MeSH ID D010959
PubChem ID 22976653
TTD Drug ID D07BQE
NDC Product Code 50242-041; 63552-041; 50242-044; 50242-085
Synonyms Tissue Plasminogen Activator | Plasminogen Activator, Tissue | Tissue Activator D-44 | Tissue Activator D 44 | Tisokinase | Tissue-Type Plasminogen Activator | Tissue Type Plasminogen Activator | TTPA | T-Plasminogen Activator | T Plasminogen Activator | Alteplase | Plasminogen Activator, Tissue-Type | Plasminogen Activator, Tissue Type | Activase | Actilyse | Lysatec rt-PA | Lysatec rt PA | Lysatec rtPA
Chemical Information
Molecular Formula C42H36N2
CAS Registry Number 177799-16-5
SMILES CC1=CC=C(C=C1)N(C2=CC=C(C=C2)C)C3=C4C=CC=CC4=C(C5=CC=CC=C53)N(C6=CC=C(C=C6)C)C7= CC=C(C=C7)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Death08.04.01.001--
Haemorrhage intracranial24.07.04.003; 17.08.01.008--
Pulmonary embolism22.06.02.001; 24.01.06.001--Not Available
Sepsis11.01.11.003--
Venous thrombosis24.01.01.008--Not Available
Haemorrhage24.07.01.002--Not Available
Peripheral embolism24.01.02.005--Not Available
The 1th Page    1    Total 1 Pages