| Pharmaceutical Information |
| Drug Name |
Aliskiren hemifumarate |
| Drug ID |
BADD_D00074 |
| Description |
Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension.[A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007.[L14018] Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in conjunction with other antihypertensive agents.[A203624] |
| Indications and Usage |
For the treatment of hypertension, to lower blood pressure. |
| Marketing Status |
Prescription |
| ATC Code |
C09XA02 |
| DrugBank ID |
DB09026
|
| KEGG ID |
D06412
|
| MeSH ID |
C446481
|
| PubChem ID |
6918427
|
| TTD Drug ID |
D03SVX
|
| NDC Product Code |
12666-0016; 70839-300; 70839-150; 14501-0062; 65372-1178; 50090-2985; 66993-142; 66993-141 |
| Synonyms |
aliskiren | rasilez | Tekturna | CGP 060536B | CGP060536B | CGP-060536B | 2(S),4(S),5(S),7(S)-N-(2-carbamoyl-2-methylpropyl)-5-amino-4-hydroxy-2,7-diisopropyl-8-(4-methoxy-3-(3-methoxypropoxy)phenyl)octanamid hemifumarate | SPP100 |
|
| Chemical Information |
| Molecular Formula |
C64H110N6O16 |
| CAS Registry Number |
173334-58-2 |
| SMILES |
CC(C)C(CC1=CC(=C(C=C1)OC)OCCCOC)CC(C(CC(C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.CC(C)C(CC
1=CC(=C(C=C1)OC)OCCCOC)CC(C(CC(C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.C(=CC(=O)O)C(=O)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
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