Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Alfentanil hydrochloride
Drug ID BADD_D00068
Description A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Indications and Usage For the management of postoperative pain and the maintenance of general anesthesia.
Marketing Status approved; illicit
ATC Code N01AH02
DrugBank ID DB00802
KEGG ID D00835
MeSH ID D015760
PubChem ID 64761
TTD Drug ID D0A3ES
NDC Product Code 17478-067
UNII 11S92G0TIW
Synonyms Alfentanil | Alfentanyl | Alfentanil Hydrochloride | R-39209 | R 39209 | R39209 | Alfenta | Limifen | Rapifen | Fanaxal
Chemical Information
Molecular Formula C21H33ClN6O3
CAS Registry Number 69049-06-5
SMILES CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCN3C(=O)N(N=N3)CC)COC.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice.
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Apnoea22.02.01.001--
Arrhythmia02.03.02.001---
Bronchospasm22.03.01.004; 10.01.03.012--
Chest discomfort02.02.02.009; 22.12.02.002; 08.01.08.019---
Chills15.05.03.016; 08.01.09.001--
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.007--
Euphoric mood19.04.02.006--
Headache17.14.01.001--
Hypercapnia22.02.02.002; 14.01.04.001---
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Laryngospasm22.04.02.002--
Movement disorder17.01.02.010---
Muscle rigidity17.05.02.005; 15.05.04.001---
Myoclonus17.02.05.008---
Nausea07.01.07.001--
Pain08.01.08.004--
Pruritus23.03.12.001--
Sedation17.02.04.005---
Somnolence19.02.05.003; 17.02.04.006--
Tachycardia02.03.02.007---
Urticaria23.04.02.001; 10.01.06.001--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Confusion postoperative19.13.01.004; 17.02.03.004; 12.02.04.001---
Postoperative respiratory distress22.02.06.006; 12.02.07.001---
Nuchal rigidity15.05.04.005; 17.05.02.006---
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