Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Alfentanil hydrochloride
Drug ID BADD_D00068
Description A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Indications and Usage For the management of postoperative pain and the maintenance of general anesthesia.
Marketing Status Prescription
ATC Code N01AH02
DrugBank ID DB00802
KEGG ID D00835
MeSH ID D015760
PubChem ID 64761
TTD Drug ID D0A3ES
NDC Product Code 17478-067; 17478-841
Synonyms Alfentanil | Alfentanyl | Alfentanil Hydrochloride | R-39209 | R 39209 | R39209 | Alfenta | Limifen | Rapifen | Fanaxal
Chemical Information
Molecular Formula C21H33ClN6O3
CAS Registry Number 69049-06-5
SMILES CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCN3C(=O)N(N=N3)CC)COC.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Apnoea22.02.01.001--
Arrhythmia02.03.02.001--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Chest discomfort22.02.08.001; 08.01.08.019; 02.02.02.009--Not Available
Chills15.05.03.016; 08.01.09.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Euphoric mood19.04.02.006--
Headache17.14.01.001--
Hypercapnia22.02.02.002; 14.01.04.001--Not Available
Hypertension24.08.02.001--
Hypotension24.06.03.002--
Laryngospasm22.04.02.002--
Movement disorder17.01.02.010--Not Available
Muscle rigidity17.05.02.005; 15.05.04.001--Not Available
Myoclonus17.02.05.008--Not Available
Nausea07.01.07.001--
Pain08.01.08.004--
Pruritus23.03.12.001--
Sedation17.02.04.005--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Tachycardia02.03.02.007--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Confusion postoperative17.02.03.004; 12.02.04.001; 19.13.01.004--Not Available
Postoperative respiratory distress22.02.06.006; 12.02.07.001--Not Available
Nuchal rigidity17.05.02.006; 15.05.04.005--Not Available
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