| ADR Ontology |
| ADR Term |
Stiff person syndrome |
| ADR ID |
BADD_A09147 |
| ADR Hierarchy |
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| Description |
A condition characterized by persistent spasms (SPASM) involving multiple muscles, primarily in the lower limbs and trunk. The illness tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that become continuous. Minor sensory stimuli, such as noise and light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. Respiration may become impaired in advanced cases. (Adams et al., Principles of Neurology, 6th ed, p1492; Neurology 1998 Jul;51(1):85-93) [MeSH] |
| MedDRA Code |
10072148 |
| MeSH ID |
D016750; D016750; D016750
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Stiff-man syndrome | Stiff person syndrome | Stiff-Person Syndrome | Stiff Person Syndrome | Syndrome, Stiff-Person | Stiff-Man Syndrome | Stiff Man Syndrome | Syndrome, Stiff-Man | Stiffman Syndrome | Syndrome, Stiffman | Stiff-Baby Syndrome | Stiff-Baby Syndromes | Syndrome, Stiff-Baby | Syndromes, Stiff-Baby | Congenital Stiff-Man Syndrome | Congenital Stiff Man Syndrome | Congenital Stiff-Man Syndromes | Stiff-Man Syndrome, Congenital | Stiff-Man Syndromes, Congenital | Syndrome, Congenital Stiff-Man | Syndromes, Congenital Stiff-Man | Congenital Stiff-Person Syndrome | Congenital Stiff-Person Syndromes | Stiff-Person Syndrome, Congenital | Stiff-Person Syndromes, Congenital | Syndrome, Congenital Stiff-Person | Syndromes, Congenital Stiff-Person | Startle Syndrome | Startle Syndromes | Syndrome, Startle | Syndromes, Startle | Moersch-Woltmann Syndrome | Moersch Woltmann Syndrome | Syndrome, Moersch-Woltmann | Stiff-Trunk Syndrome | Stiff Trunk Syndrome | Stiff-Trunk Syndromes | Syndrome, Stiff-Trunk | Syndromes, Stiff-Trunk | Familial Hyperekplexia | Familial Hyperekplexias | Hyperekplexia, Familial | Hyperekplexias, Familial | Hereditary Hyperekplexia | Hereditary Hyperekplexias | Hyperekplexia, Hereditary | Hyperekplexias, Hereditary |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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