Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Naevus flammeus
ADR ID BADD_A08890
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.05      Skin and subcutaneous tissue disorders congenital
03.05.01      Skin and subcutaneous tissue disorders congenital NEC
03.05.01.020      Naevus flammeus
23      Skin and subcutaneous tissue disorders
23.05      Pigmentation disorders
23.05.01      Hyperpigmentation disorders
23.05.01.016      Naevus flammeus
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.03      Vascular malformations and acquired anomalies
24.03.03.036      Naevus flammeus
Description A vascular malformation of developmental origin characterized pathologically by ectasia of superficial dermal capillaries, and clinically by persistent macular erythema. In the past, port wine stains have frequently been termed capillary hemangiomas, which they are not; unfortunately this confusing practice persists: HEMANGIOMA, CAPILLARY is neoplastic, a port-wine stain is non-neoplastic. Port-wine stains vary in color from fairly pale pink to deep red or purple and in size from a few millimeters to many centimeters in diameter. The face is the most frequently affected site and they are most often unilateral. (From Rook et al., Textbook of Dermatology, 5th ed, p483) [MeSH]
MedDRA Code 10067193
MeSH ID D019339
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Port wine naevus | Port wine stain | Salmon patch | Port wine nevus | Naevus flammeus | Nevus flammeus | Stork bite | Port-Wine Stain | Port Wine Stain | Port-Wine Stains | Stain, Port-Wine | Stains, Port-Wine | Nevus Flammeus
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00086Alprostadil0.005262%
BADD_D01265Levetiracetam0.002095%
BADD_D01445Metoprolol0.000093%
BADD_D02010Sertraline0.000151%
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