| ADR Ontology |
| ADR Term |
Multiple system atrophy |
| ADR ID |
BADD_A08728 |
| ADR Hierarchy |
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| Description |
A progressive neurodegenerative condition of the central and autonomic nervous systems characterized by atrophy of the preganglionic lateral horn neurons of the thoracic spinal cord. This disease is generally considered a clinical variant of MULTIPLE SYSTEM ATROPHY. Affected individuals present in the fifth or sixth decade with ORTHOSTASIS and bladder dysfunction; and later develop FECAL INCONTINENCE; anhidrosis; ATAXIA; IMPOTENCE; and alterations of tone suggestive of basal ganglia dysfunction. (From Adams et al., Principles of Neurology, 6th ed, p536) [MeSH] |
| MedDRA Code |
10064060 |
| MeSH ID |
D012791; D019578; D009849; D019578; D019578
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Shy-Drager syndrome | Olivopontocerebellar atrophy | Multiple system atrophy | Shy-Drager Syndrome | Shy Drager Syndrome | Syndrome, Shy-Drager | Syndrome, Dysautonomia-Orthostatic Hypotension | Syndrome, Dysautonomia Orthostatic Hypotension | Orthostatic Hypotension, Dysautonomic | Dysautonomic Orthostatic Hypotension | Dysautonomic Orthostatic Hypotensions | Hypotension, Dysautonomic Orthostatic | Hypotensions, Dysautonomic Orthostatic | Orthostatic Hypotensions, Dysautonomic | Dysautonomia-Orthostatic Hypotension Syndrome | Dysautonomia Orthostatic Hypotension Syndrome | Dysautonomia-Orthostatic Hypotension Syndromes | Hypotension Syndrome, Dysautonomia-Orthostatic | Hypotension Syndromes, Dysautonomia-Orthostatic | Syndromes, Dysautonomia-Orthostatic Hypotension | Autonomic Failure, Progressive | Autonomic Failures, Progressive | Failure, Progressive Autonomic | Failures, Progressive Autonomic | Progressive Autonomic Failure | Progressive Autonomic Failures | Idiopathic Orthostatic Hypotension, Shy-Drager Type | Idiopathic Orthostatic Hypotension, Shy Drager Type |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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