Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Dermatofibrosarcoma protuberans
ADR ID BADD_A08284
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.09      Musculoskeletal and connective tissue neoplasms
15.09.03      Malignant musculoskeletal and connective tissue neoplasms
15.09.03.014      Dermatofibrosarcoma protuberans
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.33      Soft tissue neoplasms malignant and unspecified
16.33.03      Fibrosarcomas malignant
16.33.03.002      Dermatofibrosarcoma protuberans
Description A sarcoma of the deep layers of the skin. The tumors are locally aggressive tends to recur but rarely metastatic. It can be classified into variants depending on the cell type tumors are derived from or by its characteristics: Pigmented variant from MELANIN-containing DERMAL DENDRITIC CELLS; Myxoid variant, myxoid STROMAL CELLS; Giant cell variant characterized by GIANT CELLS in the tumors; and Fibrosarcomatous variant chracterized by tumor areas histologically indistinguishable from FIBROSARCOMA. [MeSH]
MedDRA Code 10057070
MeSH ID D018223; D018223; D018223
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Dermatofibrosarcoma | Dermatofibrosarcoma protuberans | Dermatofibrosarcomas | Darier-Hoffmann Tumor | Darier Hoffmann Tumor | Tumor, Darier-Hoffmann | Dermatofibrosarcoma Protuberan | Dermatofibrosarcoma Protuberans | Protuberan, Dermatofibrosarcoma | Protuberans, Dermatofibrosarcoma | Darier-Ferrand Tumor | Darier Ferrand Tumor | Tumor, Darier-Ferrand | Metastatic Dermatofibrosarcoma Protuberans | Dermatofibrosarcoma Protuberan, Metastatic | Dermatofibrosarcoma Protuberans, Metastatic | Metastatic Dermatofibrosarcoma Protuberan | Protuberan, Metastatic Dermatofibrosarcoma | Protuberans, Metastatic Dermatofibrosarcoma | FS-DFSP | Fibrosarcomatous Dermatofibrosarcoma Protuberans | Dermatofibrosarcoma Protuberans, Fibrosarcomatous | Dermatofibrosarcoma Protuberan, Fibrosarcomatous | Fibrosarcomatous Dermatofibrosarcoma Protuberan | Protuberan, Fibrosarcomatous Dermatofibrosarcoma | Protuberans, Fibrosarcomatous Dermatofibrosarcoma | DFSP, Fibrosarcomatous | DFSPs, Fibrosarcomatous | Fibrosarcomatous DFSP | Fibrosarcomatous DFSPs | Giant Cell Fibroblastoma | Cell Fibroblastoma, Giant | Cell Fibroblastomas, Giant | Fibroblastoma, Giant Cell | Fibroblastomas, Giant Cell | Giant Cell Fibroblastomas | Giant Dermatofibrosarcoma Protuberans | Dermatofibrosarcoma Protuberan, Giant | Dermatofibrosarcoma Protuberans, Giant | Giant Dermatofibrosarcoma Protuberan | Protuberan, Giant Dermatofibrosarcoma | Protuberans, Giant Dermatofibrosarcoma | DFSP, Juvenile | DFSPs, Juvenile | Juvenile DFSP | Juvenile DFSPs | Familial Dermatofibrosarcoma Protuberans | Dermatofibrosarcoma Protuberans, Familial | Dermatofibrosarcoma Protuberan, Familial | Familial Dermatofibrosarcoma Protuberan | Protuberan, Familial Dermatofibrosarcoma | Protuberans, Familial Dermatofibrosarcoma | Dermatofibrosarcoma Protuberans, Giant Cell | Dermatofibrosarcoma Protuberans, Myxoid | Dermatofibrosarcoma Protuberan, Myxoid | Myxoid Dermatofibrosarcoma Protuberan | Myxoid Dermatofibrosarcoma Protuberans | Protuberan, Myxoid Dermatofibrosarcoma | Protuberans, Myxoid Dermatofibrosarcoma | DFSP, Myxoid | DFSPs, Myxoid | Myxoid DFSP | Myxoid DFSPs | Dermatofibrosarcoma Protuberans, Pigmented | Dermatofibrosarcoma Protuberan, Pigmented | Pigmented Dermatofibrosarcoma Protuberan | Pigmented Dermatofibrosarcoma Protuberans | Protuberan, Pigmented Dermatofibrosarcoma | Protuberans, Pigmented Dermatofibrosarcoma | Bednar's Tumor | Bednars Tumor | Tumor, Bednar's | DFSP, Pigmented | DFSPs, Pigmented | Pigmented DFSP | Pigmented DFSPs | Bednar Tumor | Tumor, Bednar
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00312Bupropion0.000088%
BADD_D01687Pazopanib0.000139%
BADD_D02464Fingolimod0.001158%
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