Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Transposition of the great vessels
ADR ID BADD_A07775
ADR Hierarchy
02      Cardiac disorders
02.08      Congenital cardiac disorders
02.08.03      Congenital cardiac malpositions and transpositions
02.08.03.005      Transposition of the great vessels
03      Congenital, familial and genetic disorders
03.07      Cardiac and vascular disorders congenital
03.07.08      Great vessel disorders congenital
03.07.08.009      Transposition of the great vessels
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.03      Vascular malformations and acquired anomalies
24.03.03.042      Transposition of the great vessels
Description A congenital cardiovascular malformation in which the AORTA arises entirely from the RIGHT VENTRICLE, and the PULMONARY ARTERY arises from the LEFT VENTRICLE. Consequently, the pulmonary and the systemic circulations are parallel and not sequential, so that the venous return from the peripheral circulation is re-circulated by the right ventricle via aorta to the systemic circulation without being oxygenated in the lungs. This is a potentially lethal form of heart disease in newborns and infants. [MeSH]
MedDRA Code 10044443
MeSH ID D014188
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Aorta-pulmonary art transposition | Aorta-pulmonary arterial transposition | Complete transposition of great vessels | Other transposition of great vessels | Transposition aorta-pulmonary artery | Transposition of aorta | Transposition of great vessels | Transposition of the great vessels | Transposition of Great Vessels | Great Vessels Transposition | Great Vessels Transpositions | Dextro-Looped Transposition of the Great Arteries | Dextro Looped Transposition of the Great Arteries | Transposition of Great Arteries | Great Arteries Transposition | Great Arteries Transpositions
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00312Bupropion0.000092%
BADD_D00475Citalopram0.000500%
BADD_D00680Dimethyl fumarate0.001834%
BADD_D00809Escitalopram0.000807%
BADD_D00912Fluconazole0.000619%
BADD_D00932Fluoxetine0.000318%
BADD_D01243Lamotrigine0.000387%
BADD_D01401Metformin0.000143%
BADD_D01617Ondansetron0.000699%
BADD_D01627Oseltamivir0.000145%
BADD_D01679Paroxetine0.000463%
BADD_D02010Sertraline0.000158%
BADD_D02346Venlafaxine0.000447%
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