Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Craniocerebral injury
ADR ID BADD_A06639
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.01      Injuries NEC
12.01.10      Cerebral injuries NEC
12.01.10.012      Craniocerebral injury
17      Nervous system disorders
17.11      Structural brain disorders
17.11.01      Structural brain disorders NEC
17.11.01.007      Craniocerebral injury
Description Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage. [MeSH]
MedDRA Code 10070976
MeSH ID D006259; D006259; D016489; D000070642; D006259; D006259; D020197
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Brain damage (traumatic) | Intcran inj of oth and unspec nature, w/o ment of open intcran wound, prol loc and rtrn to pecl | Intcran inj of oth and unspec nature, w/o ment of open intcran wound, prol loc, w/o rtrn to pecl | Intcran inj of oth and unspec nature, w/o ment of open intcran wound, with brief loc | Intcran inj of oth and unspec nature, w/o ment of open intcran wound, with concus, unspec | Intcran inj of oth and unspec nature, w/o ment of open intcran wound, with loc of unspec dura | Intcran inj of oth and unspec nature, w/o ment of open intcran wound, with moderate loc | Intcran inj of oth and unspec nature, w/o ment of open intcran wound, with no loc | Intcran inj of oth and unspec nature, w/o ment of open intcran wound, with state of cons unspec | Intcran inj of oth and unspec nature, with open intcran wound, with brief loc | Intcran inj of oth and unspec nature, with open intcran wound, with concussion, unspec | Intcran inj of oth and unspec nature, with open intcran wound, with loc of unspec duration | Intcran inj of oth and unspec nature, with open intcran wound, with moderate loc | Intcran inj of oth and unspec nature, with open intcran wound, with no loc | Intcran inj of oth and unspec nature, with open intcran wound, with prol loc and rtrn to pecl | Intcran inj of oth and unspec nature, with open intcran wound, with prol loc, w/o rtrn to pecl | Intcran inj of oth and unspec nature, with open intcran wound, with state of consciousness unspec | Intracranial injury NOS | Intracranial injury of other and unspecified nature | Intracranial injury of other and unspecified nature with open intracranial wound | Intracranial injury of other and unspecified nature without mention of open intracranial wound | Closed head injury | Traumatic brain damage | Traumatic brain injury | Intracranial injury | Craniocerebral injury | Penetrating head injury | Craniocerebral Trauma | Craniocerebral Traumas | Trauma, Craniocerebral | Traumas, Craniocerebral | Head Injuries | Injuries, Craniocerebral | Trauma, Head | Craniocerebral Injuries | Craniocerebral Injury | Injury, Craniocerebral | Injuries, Head | Head Injury | Injury, Head | Head Trauma | Head Traumas | Traumas, Head | Parietal Region Trauma | Parietal Region Traumas | Region Trauma, Parietal | Region Traumas, Parietal | Trauma, Parietal Region | Traumas, Parietal Region | Crushing Skull Injury | Crushing Skull Injuries | Skull Injuries, Crushing | Skull Injury, Crushing | Head Injury, Minor | Head Injuries, Minor | Injuries, Minor Head | Injury, Minor Head | Minor Head Injuries | Minor Head Injury | Head Injuries, Multiple | Head Injury, Multiple | Injuries, Multiple Head | Injury, Multiple Head | Multiple Head Injury | Multiple Head Injuries | Head Injury, Open | Head Injuries, Open | Injuries, Open Head | Injury, Open Head | Open Head Injuries | Open Head Injury | Head Injury, Superficial | Head Injuries, Superficial | Injuries, Superficial Head | Injury, Superficial Head | Superficial Head Injuries | Superficial Head Injury | Occipital Region Trauma | Occipital Region Traumas | Region Trauma, Occipital | Region Traumas, Occipital | Trauma, Occipital Region | Traumas, Occipital Region | Occipital Trauma | Occipital Traumas | Trauma, Occipital | Traumas, Occipital | Temporal Region Trauma | Temporal Region Traumas | Trauma, Temporal Region | Traumas, Temporal Region | Frontal Region Trauma | Frontal Region Traumas | Region Trauma, Frontal | Region Traumas, Frontal | Trauma, Frontal Region | Traumas, Frontal Region | Forehead Trauma | Forehead Traumas | Trauma, Forehead | Traumas, Forehead
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00014Abiraterone0.000384%
BADD_D00066Alendronic acid0.000707%
BADD_D00085Alprazolam0.000084%
BADD_D00151Apixaban0.002252%
BADD_D00165Aripiprazole0.001335%
BADD_D00194Azacitidine0.000139%
BADD_D00312Bupropion0.000132%
BADD_D00405Ceftriaxone0.020426%
BADD_D00410Celecoxib0.000230%
BADD_D00504Clopidogrel0.000196%
BADD_D00511Clozapine0.014012%
BADD_D00564Dabigatran etexilate0.024789%
BADD_D00574Dalfampridine0.002614%
BADD_D00648Diazepam0.000213%
BADD_D00794Ergocalciferol0.000102%
BADD_D00898Finasteride0.000428%
BADD_D00979Furosemide0.000095%
BADD_D01243Lamotrigine0.000516%
BADD_D01253Lenalidomide--
BADD_D01265Levetiracetam0.000571%
BADD_D01401Metformin0.000026%
BADD_D01567Nilotinib0.000278%
BADD_D01617Ondansetron0.000150%
BADD_D01637Oxcarbazepine--
BADD_D01835Pregabalin0.000472%
BADD_D01933Ribavirin0.007095%
BADD_D01954Rivaroxaban0.003926%
BADD_D02047Sodium oxybate0.002422%
BADD_D02214Ticagrelor0.001259%
BADD_D02254Tramadol0.000063%
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