Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Macrophage activation
ADR ID BADD_A04922
ADR Hierarchy
25      Surgical and medical procedures
25.01      Therapeutic procedures and supportive care NEC
25.01.02      Therapeutic procedures NEC
25.01.02.005      Macrophage activation
Description The process of altering the morphology and functional activity of macrophages so that they become avidly phagocytic. It is initiated by lymphokines, such as the macrophage activation factor (MAF) and the macrophage migration-inhibitory factor (MMIF), immune complexes, C3b, and various peptides, polysaccharides, and immunologic adjuvants. [MeSH]
MedDRA Code 10050206
MeSH ID D008262
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Macrophage activation | Macrophage Activation | Activation, Macrophage | Activations, Macrophage | Macrophage Activations
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00281Bleomycin sulfate--
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