Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Dupuytren's contracture
ADR ID BADD_A01356
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.03      Musculoskeletal and connective tissue disorders NEC
15.03.03      Musculoskeletal and connective tissue infections and inflammations NEC
15.03.03.003      Dupuytren's contracture
Description A fibromatosis of the palmar fascia characterized by thickening and contracture of the fibrous bands on the palmar surfaces of the hand and fingers. It arises most commonly in men between the ages of 30 and 50. [MeSH]
MedDRA Code 10013872
MeSH ID D004387; D004387; D004387
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Contracture Dupytren's | Contracture of palmar fascia | Dupuytren's contracture | Palmar fibromatosis | Dupuytren Contracture | Contracture, Dupuytren | Dupuytren's Contracture | Contracture, Dupuytren's | Dupuytrens Contracture | Fibromatosis, Palmar | Palmar Fibromatosis | Dupuytren's Disease | Dupuytren Disease | Dupuytrens Disease
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000202%
BADD_D00142Anastrozole0.000754%
BADD_D01285Levothyroxine0.000023%
BADD_D01567Nilotinib0.000799%
BADD_D01765Phenytoin--
BADD_D01840Primidone0.003092%
BADD_D01909Ramipril0.000400%
BADD_D01966Ropinirole--
BADD_D02219Timolol0.000658%
BADD_D02236Tofacitinib0.001737%
BADD_D02344Vemurafenib0.001299%
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