| ADR Ontology |
| ADR Term |
Activated partial thromboplastin time |
| ADR ID |
BADD_A00067 |
| ADR Hierarchy |
|
| Description |
The time required for the appearance of FIBRIN strands following the mixing of PLASMA with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of BLOOD COAGULATION. It is used as a screening test and to monitor HEPARIN therapy. [MeSH] |
| MedDRA Code |
10000630 |
| MeSH ID |
D010314
|
|
ADR Severity Grade (FAERS)
|
|
|
ADR Severity Grade (CTCAE)
|
Not Available
|
| Synonym |
| Activated partial thromboplastin time | APTT | Partial prothrombin time | Partial Thromboplastin Time | Thromboplastin Time, Partial | Activated Partial Thromboplastin Time | Kaolin-Cephalin Coagulation Time | Coagulation Time, Kaolin-Cephalin | Kaolin Cephalin Coagulation Time | Coagulation Time, Cephalin-Kaolin | Coagulation Time, Cephalin Kaolin | Cephalin-Kaolin Coagulation Time | Cephalin Kaolin Coagulation Time |
|
|
| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
|
| Drugs Leading to the ADR |
| Drug ID | Drug Name | ADR Frequency (FAERS) | ADR Severity Grade (FAERS) | | BADD_D00564 | Dabigatran etexilate | 0.002110% | | | BADD_D02217 | Tigecycline | - | - |
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