Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Adrenocortical carcinoma
ADR ID BADD_A09438
ADR Hierarchy
05      Endocrine disorders
05.01      Adrenal gland disorders
05.01.04      Adrenal neoplasms
05.01.04.010      Adrenocortical carcinoma
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.24      Endocrine neoplasms malignant and unspecified
16.24.06      Adrenal neoplasms malignant
16.24.06.002      Adrenocortical carcinoma
Description A malignant neoplasm of the ADRENAL CORTEX. Adrenocortical carcinomas are unencapsulated anaplastic (ANAPLASIA) masses sometimes exceeding 20 cm or 200 g. They are more likely to be functional than nonfunctional, and produce ADRENAL CORTEX HORMONES that may result in hypercortisolism (CUSHING SYNDROME); HYPERALDOSTERONISM; and/or VIRILISM. [MeSH]
MedDRA Code 10001388
MeSH ID D018268
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Adrenocortical carcinoma | Anaplastic adrenocortical carcinoma | Differentiated adrenocortical carcinoma | Adrenocortical Carcinoma | Adrenocortical Carcinomas | Carcinomas, Adrenocortical | Carcinoma, Adrenocortical | Carcinoma, Adrenal Cortical | Adrenal Cortical Carcinoma | Adrenal Cortical Carcinomas | Carcinomas, Adrenal Cortical
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02058Sorafenib0.000112%
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