Adverse Drug Reaction Classification System

ADReCS is subject to periodic updates. Therefore, do visit back on this database to get the latest information whenever needed.

2023/03/16

UPDATE! The ADR severity and frequency data based on FAERS have been updated, and the dataset of quantitative features can now be downloaded from the DOWNLOAD page.

2022/06/21

UPDATE! ADReCS has updated drug ID matching information with PubChem, DrugBank, KEGG, and MeSH.

2021/05/20

UPDATE! ADReCS has updated to version 3.1 (ADReCS v3.1).The ADR frequency and severity based on FAERS have been integrated into ADReCS v3.1.

2020/12/25

UPDATE! Check and optimize the data in ADReCS.

2019/05/15

UPDATE! ADReCS has updated to version 3.0 (ADReCS v3.0). 194 new drugs, 6,111 new ADRs(PT) and corresponding 466,625 new Drug-ADR pairs from The FDA Adverse Event Reporting System (FAERS) is filtered and integrated into ADReCS v3.0.

2018/08/14

UPDATE! A mirror site (http://www.bio-add.org/ADReCS/index.jsp) is deployed for more availability and stable access.

2018/05/20

UPDATE! ADReCS v2.2 has been released. including 2,399 drugs, 5,160 PTs, 1,333 HLTs, 327 HLGTs and 27 SOCs. The severity grades of ADRs, ADR-related proteins and tools for ADR similarity searching and structure similarity searching have been integrated into ADReCS v2.2.

2017/09/08

UPDATE! ADReCS has updated to version 2.0 (ADReCS v2.0). In ADReCS v2.0, we redesigned an interface to enhance data visualization and optimized code to Improve search efficiency.

2017/06/25

UPDATE! Add a new target database ADReCS-Target Beta including 27,484 ADR-gene pairs, 2,613 ADR-variation pairs and 1,710 ADR-protein pairs. The version 1.7 is ready for service.

2017/05/21

UPDATE! Add 185 new PTs and 9 new HLTs. The version 1.61 is ready for service.

2016/04/11

UPDATE! Add 320 new drugs. The version 1.6 is ready for service.

2015/06/25

UPDATE! Add 26 new drugs and 214 new ADR terms.The version 1.4 is ready for service.

2014/10/31

The ADReCS manuscript is now online at Nucleic Acids Research! ADReCS: an ontology database for aiding standardization and hierarchical classification of adverse drug reaction terms.

2014/09/02

The ADReCS manuscript is now online at Nucleic Acids Research! The SMILES and structure search tools has been updated.

2014/07/01

ADReCS is available for query result download.

2014/06/14

The version 1.2 is ready for service.

2014/05/23

ADReCS is available for data download.

2014/04/28

The SMILES and structure search tools has been implemented.

2013/12/15

The version 1.0 is ready for service.