| Pharmaceutical Information |
| Drug Name |
Plecanatide |
| Drug ID |
BADD_D02516 |
| Description |
Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC). It should not be used in children less than six years of age, and should be avoided in patients six years to 18 years of age |
| Indications and Usage |
Plecanatide stimulates intestinal fluid secretions in the gastrointestinal tract to support regular bowel function. Plecanatide, taken orally once daily, works locally in the upper GI tract to stimulate secretion of intestinal fluid and support regular bowel function. |
| Marketing Status |
Not Available |
| ATC Code |
A06AX07 |
| DrugBank ID |
DB13170
|
| KEGG ID |
D09948
|
| MeSH ID |
C584575
|
| PubChem ID |
70693500
|
| TTD Drug ID |
D07FEC
|
| NDC Product Code |
41524-0014; 52076-6226; 65015-891; 65649-003; 59651-619; 69766-071; 70194-003 |
| Synonyms |
plecanatide | SP-304 | Trulance |
|
| Chemical Information |
| Molecular Formula |
C65H104N18O26S4 |
| CAS Registry Number |
467426-54-6 |
| SMILES |
CC1C(=O)NC2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(NC(=O)CNC(=O)C(NC2=O)C(C)O)C(=O)N
C(CC(C)C)C(=O)O)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)C(C)C)CC(=O)N)C(C)C)CC(C)C)CCC(=
O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(=O)N)N |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
