Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Hydrogen peroxide
Drug ID BADD_D02479
Description Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it may undergo potentially explosive thermal decomposition. Hydrogen peroxide is formed in the body of mammals during reduction of oxygen either directly in a two-electron transfer reaction [L2024]. As a natural product of metabolism, it readily undergoes decomposition by catalase in normal cells [L2024]. Due to its potent and broad-spectrum antimicrobial actions, hydrogen peroxide is used in both liquid and gas form for preservative, disinfection and sterilization applications as an oxidative biocide [A32369]. It is used in industrial and cosmetic applications as a bleaching agent. Hydrogen peroxide is also considered as a generally recognized as safe compound by the FDA [L2024]; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing agent in products containing dried eggs, dried egg whites, and dried egg yolks.
Indications and Usage Indicated to be used as a disinfectant and sterilizer.
Marketing Status Not Available
ATC Code A01AB02; D08AX01; D11AX25; S02AA06
DrugBank ID DB11091
KEGG ID D00008
MeSH ID D006861
PubChem ID 784
TTD Drug ID D03IDU
NDC Product Code 37012-871; 81577-4000; 0363-0085; 53329-983; 63868-184; 81577-5000; 55316-871; 55549-300; 10733-800; 46994-871; 63940-871; 69612-018; 47682-304; 81577-3000; 47682-259; 55315-268; 53329-086; 11822-0871; 12745-205; 53329-980; 39892-0710; 53943-871; 43128-001; 67091-407; 66715-6846; 70000-0022; 49035-268; 53329-981; 10202-001; 51628-4231; 41163-871; 81794-600; 59883-018; 39892-0700; 69842-008; 68599-2305; 50804-156; 41250-871; 51316-078; 11673-268; 74830-002; 68062-2292; 73660-001; 81057-302; 0404-0001; 33992-0871; 49580-0268; 44224-3122; 67751-001; 81057-301; 36800-214; 47682-275; 70000-0500; 53943-099; 63517-450; 69950-005; 73573-015; 74556-001; 61734-010; 41190-871; 69612-004; 30142-871; 20276-300; 81794-800; 56062-871; 65055-501; 0869-0871; 55301-871; 81577-1000; 74719-0005; 69256-268; 70812-010; 81238-5400; 11822-1462; 41250-750; 61715-119; 78495-152; 78495-162; 0802-1113; 42961-016; 61010-5400; 21130-871; 52380-0013; 17129-001; 47682-334; 72288-871; 49452-3600; 12745-202; 72655-200; 11673-327; 50594-871; 55319-871; 55910-268; 53942-871; 67091-101; 53462-075; 81794-700; 36800-871; 73700-003; 11673-871; 69612-012; 63868-147; 15127-871; 76176-111; 60319-5001; 73408-257; 62011-0267; 61504-871; 49681-016; 47682-324; 81307-020; 81794-900; 53175-001; 59883-017; 67326-354; 57243-871; 50804-871; 55910-871; 67860-871; 68196-268; 70082-111; 81577-2000; 0869-0462; 69612-622; 69951-002; 72476-942; 80668-313; 11822-3155; 73134-060; 47682-257; 51532-5400; 0363-0871; 68016-871; 76772-023; 10565-001; 41250-268; 76772-028; 67326-353; 59779-871; 81577-6000; 76162-327; 37808-871; 49738-620; 60319-1001; 49348-179; 68062-2253; 55549-301; 63941-871; 52000-025; 46122-334; 49035-267; 0363-0268; 42681-6414; 0126-0083; 51048-040; 68599-2301; 49035-871; 37205-871; 55239-450; 0363-0267; 69612-001
Synonyms Hydrogen Peroxide | Peroxide, Hydrogen | Hydrogen Peroxide (H2O2) | Hydroperoxide | Superoxol | Oxydol | Perhydrol
Chemical Information
Molecular Formula H2O2
CAS Registry Number 7722-84-1
SMILES OO
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.034702%
Abdominal tenderness07.01.05.0040.034702%Not Available
Air embolism24.01.01.001; 12.02.05.0080.034702%Not Available
Bezoar07.11.01.0080.034702%Not Available
Erythema23.03.06.0010.069404%Not Available
Eye swelling06.08.03.0030.052053%Not Available
Eyelid oedema23.04.01.003; 10.01.05.001; 06.04.04.0040.086755%Not Available
Hair colour changes23.02.06.0010.034702%
Hypertrophic scar23.01.03.0030.086755%Not Available
Nausea07.01.07.0010.052053%
Oedema14.05.06.010; 08.01.07.0060.052053%Not Available
Pain08.01.08.0040.034702%
Paraesthesia17.02.06.0050.034702%
Skin hyperpigmentation23.05.01.0030.034702%
Vomiting07.01.07.0030.034702%
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