| Pharmaceutical Information |
| Drug Name |
Procaine benzylpenicillin |
| Drug ID |
BADD_D02478 |
| Description |
Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic. It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent procaine in equimolar amounts. Procaine benzylpenicillin is administered by deep intramuscular injection. It is slowly absorbed and hydrolyzed to benzylpenicillin. This drug is used where prolonged exposure to benzylpenicillin at a low concentration is required. This combination is aimed at reducing the pain and discomfort associated with a large intramuscular injection of penicillin. It is widely used in veterinary settings. Benzylpenicillin is active against a wide range of organisms and is the drug of first choice for many infections. |
| Indications and Usage |
For the treatment of a number of bacterial infections such as syphilis, anthrax, mouth infections, pneumonia and diphtheria. |
| Marketing Status |
Not Available |
| ATC Code |
J01CE01; S01AA14 |
| DrugBank ID |
DB09320
|
| KEGG ID |
D02461
|
| MeSH ID |
D010402
|
| PubChem ID |
5903
|
| TTD Drug ID |
D0A5LH
|
| NDC Product Code |
Not Available |
| Synonyms |
Penicillin G Procaine | G Procaine, Penicillin | Procaine, Penicillin G | Benzylpenicillin Procaine | Procaine, Benzylpenicillin | Procaine Penicillin | Penicillin, Procaine | Jenacillin |
|
| Chemical Information |
| Molecular Formula |
C29H38N4O6S |
| CAS Registry Number |
54-35-3 |
| SMILES |
CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.CC1(C(N2C(S1)C(C2=O)NC(=O)CC3=CC=CC=C3)C(=O)O)C |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Anaphylactic reaction | 24.06.03.006; 10.01.07.001 | 0.000319% | | | | Anxiety | 19.06.02.002 | 0.000213% | | | | Dizziness | 24.06.02.007; 17.02.05.003; 02.01.02.004 | 0.000213% | | | | Drug hypersensitivity | 10.01.01.001 | 0.002448% | | Not Available | | Rash | 23.03.13.001 | 0.000319% | | Not Available | | Urticaria | 23.04.02.001; 10.01.06.001 | 0.000319% | | |
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