Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxygen
Drug ID BADD_D02471
Description Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric conditions.
Indications and Usage Oxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption such as respiratory illnesses, trauma, poisonings and drug overdoses. Oxygen therapy tries to achieve hyperoxia [L745] to reduce the extent of hypoxia-induced tissue damage and malfunction.
Marketing Status Not Available
ATC Code V03AN01
DrugBank ID DB09140
KEGG ID D00003
MeSH ID D010100
PubChem ID 977
TTD Drug ID Not Available
NDC Product Code 71408-001; 76091-002; 49154-001; 55703-001; 62377-001; 53952-001; 11928-002; 62671-001; 52568-001; 43621-001; 60367-002; 64395-0001; 57999-001; 72760-001; 68623-123; 59387-001; 51319-072; 53663-0001; 62066-001; 49221-0030; 66083-741; 82401-001; 60768-001; 51486-720; 67061-001; 62234-001; 51319-073; 61865-001; 62686-001; 55913-001; 73055-001; 60596-1072; 56130-002; 61830-001; 49204-001; 72457-003; 10297-001; 44517-001; 42821-001; 11054-009; 29181-001; 62481-4565; 61420-0001; 20942-672; 69024-001; 62914-1000; 19218-0005; 58049-123; 69216-001; 70951-123; 54451-001; 59788-001; 45405-001; 70323-123; 72661-123; 19218-0002; 67525-100; 59247-001; 63674-001; 65603-100; 65336-001; 19218-0004; 62118-001; 73266-001; 59087-001; 14214-0123; 62486-130; 63560-001; 72692-123; 66586-1073; 69534-001; 60568-123; 58722-9094; 64075-123; 10482-002; 10412-0001; 39313-001; 68877-001; 10073-111; 61776-0001; 58632-001; 25373-001; 54182-001; 10526-005; 65077-001; 65297-001; 80268-001; 72746-0001; 62273-001; 72807-001; 81313-001; 63970-001; 52698-001; 44076-010; 15055-001; 60980-002; 61398-0828; 55728-100; 48546-0006; 51475-001; 81734-001; 50153-110; 55151-123; 51887-720; 14080-001; 63144-001; 46123-001; 58089-001; 49575-001; 42068-001; 61362-2150; 58700-001; 49479-722; 66228-001; 61426-123; 19218-0001; 65386-0001; 57957-0007; 69241-001; 11988-001; 58125-0001; 24887-001; 13826-001; 52374-011; 60971-1176; 46123-045; 62715-0001; 73012-001; 61128-001; 62179-1234; 59579-001; 19218-0008; 10698-0001; 64140-101; 55785-123; 52374-101; 19979-000; 80792-001; 63862-011; 67932-1313; 48546-0002; 66754-001; 54316-123; 20703-002; 67573-0104; 10942-2001; 62598-001; 68769-002; 72574-001; 76349-001; 81676-001; 76831-001; 49798-001; 67905-0001; 42914-001; 70097-001; 11324-721; 51051-003; 11401-6994; 17575-001; 10690-001; 58247-001; 72817-001; 44363-1815; 80421-100; 58128-0001; 62097-9937; 50505-001; 73468-005; 63553-001; 19218-0009; 50699-1072; 54706-0001; 67477-001; 66890-990; 65868-001; 23650-001; 63418-0001; 13859-001; 54202-001; 60779-001; 43734-002; 50322-005; 52003-011; 66767-999; 55858-001; 73422-001; 72713-123; 62447-0011; 54384-1073; 69075-001; 60184-001; 64545-0001; 52374-001; 59842-012; 10221-001; 58755-0001; 62581-1234; 19218-0006; 50597-001; 72987-001; 43734-001; 53854-123; 72814-001; 10492-001; 73037-001; 72995-001; 49799-001; 73078-001; 20479-0682; 59378-001; 80650-001; 42602-001; 60833-001; 66503-001; 64952-002; 60849-123; 61580-123; 81681-001; 21220-119; 64464-001; 63138-120; 63978-001; 73073-001; 40097-001; 71227-001; 70313-001; 70291-1000; 58662-0001; 43713-001; 68317-001; 72908-001; 54619-0001; 72710-123; 76056-001; 55037-113; 53425-001; 67711-001; 42887-001; 61903-001; 70300-001; 72973-001; 72637-001; 58722-9093; 54832-0001; 68794-001; 61869-0001; 54218-500; 58878-001; 65010-001; 11324-001; 66961-100; 66345-001; 24312-001; 20175-072; 26866-001; 59336-001; 68540-001; 31462-001; 62371-1234; 66487-001; 18482-018; 55322-0001; 73087-001; 19218-0003; 34940-004; 65208-123; 63173-001; 46123-002; 73093-001; 72706-123; 60560-1072; 70977-001; 81700-001; 64097-0001; 42241-001; 72862-001; 81287-001; 59924-001; 51960-001; 73543-001; 55050-0011; 64203-020; 64920-0001; 52142-001; 59522-001; 11056-001; 50063-001; 72662-123; 69286-001; 10218-001; 68796-5626; 52346-013; 65464-001; 49653-003; 44356-0001; 67506-001; 82007-000; 65257-001; 14784-001
Synonyms Oxygen | Oxygen-16 | Oxygen 16 | Dioxygen
Chemical Information
Molecular Formula O2
CAS Registry Number 7782-44-7
SMILES O=O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acute pulmonary oedema22.01.03.005; 02.05.02.0040.005831%Not Available
Acute respiratory distress syndrome22.01.03.0010.003042%
Acute respiratory failure14.01.04.004; 22.02.06.0010.001521%Not Available
Anaemia01.03.02.0010.011662%
Anaphylactic reaction24.06.03.006; 10.01.07.0010.005831%
Anxiety19.06.02.0020.011662%
Apnoea22.02.01.0010.005831%
Aspiration22.02.07.0070.005831%
Asthma10.01.03.010; 22.03.01.0020.008747%Not Available
Blood glucose increased13.02.02.0020.005831%Not Available
C-reactive protein increased13.09.01.0070.005831%Not Available
Cardiac arrest02.03.04.0010.004564%
Cardiac failure02.05.01.0010.003042%
Cardiac failure congestive02.05.01.002--Not Available
Cardio-respiratory arrest22.02.06.007; 02.03.04.0020.001521%Not Available
Cardiogenic shock24.06.02.006; 02.05.01.0030.005831%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest discomfort22.02.08.001; 02.02.02.009; 08.01.08.0190.005831%Not Available
Chills08.01.09.001; 15.05.03.0160.005831%
Cholelithiasis09.03.01.0020.003803%Not Available
Chronic obstructive pulmonary disease22.03.01.0070.002282%Not Available
Coma17.02.09.0010.005831%Not Available
Confusional state19.13.01.001; 17.02.03.005--
Cough22.02.03.0010.011662%
Cyanosis24.03.01.007; 22.02.02.007; 02.01.02.0020.003042%
Death08.04.01.001--
Diarrhoea07.02.01.001--
Drug abuse19.07.02.0100.001521%Not Available
Dysphonia17.02.08.004; 22.02.05.005; 19.19.03.0020.005831%
Dyspnoea22.02.01.004; 02.01.03.0020.061227%
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