Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Aclidinium
Drug ID BADD_D02465
Description Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
Indications and Usage Aclidinium bromide inhalation powder is indicated for the long-term, maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
Marketing Status Not Available
ATC Code Not Available
DrugBank ID DB08897
KEGG ID Not Available
MeSH ID Not Available
PubChem ID 11434515
TTD Drug ID D0VP1V
NDC Product Code Not Available
Synonyms Not Available
Chemical Information
Molecular Formula C26H30NO4S2+
CAS Registry Number 727649-81-2
SMILES C1C[N+]2(CCC1C(C2)OC(=O)C(C3=CC=CS3)(C4=CC=CS4)O)CCCOC5=CC=CC=C5
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Insomnia19.02.01.002; 17.15.03.002--
Joint swelling15.01.02.0040.001989%Not Available
Lip swelling23.04.01.007; 10.01.05.005; 07.05.04.0050.001989%Not Available
Loss of consciousness17.02.04.0040.002984%Not Available
Lung disorder22.02.07.0010.001989%Not Available
Malaise08.01.01.0030.008952%
Memory impairment19.20.01.003; 17.03.02.0030.002984%
Muscular weakness17.05.03.005; 15.05.06.0010.001989%
Nausea07.01.07.001--
Oedema mouth23.04.01.008; 10.01.05.006; 07.05.04.0010.001989%Not Available
Oral pain07.05.03.0020.001989%
Pneumonia11.01.09.003; 22.07.01.0030.006963%Not Available
Pruritus23.03.12.0010.003979%
Rash23.03.13.0010.005968%Not Available
Rash pruritic23.03.12.0020.002984%Not Available
Respiration abnormal22.02.08.0110.001989%Not Available
Respiratory disorder22.02.07.0020.001989%Not Available
Somnolence19.02.05.003; 17.02.04.006--
Stomatitis07.05.06.0050.001989%
Swollen tongue23.04.01.014; 10.01.05.015; 07.14.02.0030.002984%Not Available
Syncope17.02.04.008; 24.06.02.012; 02.01.02.0080.001989%
Tachycardia02.03.02.0070.002984%Not Available
Throat irritation22.02.05.013; 07.05.03.0040.003979%Not Available
Throat tightness22.02.05.015; 19.01.02.0050.001989%Not Available
Tremor17.01.06.0020.001989%
Urinary retention20.02.02.0110.004973%
Urticaria10.01.06.001; 23.04.02.0010.002984%
Vision blurred17.17.01.010; 06.02.06.0070.002984%
Wheezing22.03.01.0090.004973%
Hypoacusis04.02.01.0060.003979%
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