Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Solifenacin
Drug ID BADD_D02445
Description Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency.[L7511] It has a long duration of action as it is usually taken once daily.[L7511] Solifenacin was granted FDA approval on 19 November 2004.[L7511]
Indications and Usage For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency.
Marketing Status Not Available
ATC Code G04BD08
DrugBank ID DB01591
KEGG ID D08522
MeSH ID D000069464
PubChem ID 154059
NDC Product Code 51248-150; 51248-151; 54868-5398; 54868-4705; 68151-5406; 70518-1866; 50090-0972; 55154-3877; 55154-3878; 54569-5790; 55154-3875; 55154-3876
Brand Vesikur
Synonym Solifenacin Succinate | Succinate, Solifenacin | Quinuclidin-3'-yl-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate monosuccinate | YM905 | YM 905 | 905, YM | Vesicare | Solifenacin | 2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-1-phenyl-,1- azabicyclo(2.2.2)oct-3-yl ester, (R-(R*,S*))-
Chemical Information
Molecular Formula C23H26N2O2
CAS Registry Number 242478-37-1
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Accommodation disorder06.02.04.001--Not Available
Acute myocardial infarction24.04.04.001; Available
Acute pulmonary oedema02.05.02.004; Available
Ageusia17.02.07.001; Available
Agranulocytosis01.02.03.001--Not Available
Amylase increased13.05.01.009--
Anaphylactic reaction24.06.03.006;
Angina pectoris24.04.04.002;
Angioedema23.04.01.001; Available
Anticholinergic syndrome17.05.01.001--Not Available
Anuria20.01.03.002--Not Available
Arrhythmia02.03.02.001--Not Available
Arteriosclerosis coronary artery24.04.04.012; Available
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.002--
Autoimmune hepatitis10.04.09.001; Available
Back pain15.03.04.005--
Basedow's disease10.04.08.004;; Available
Bladder cancer16.08.01.001; Available
Blood glucose increased13.02.02.002--Not Available
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