Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rasagiline
Drug ID BADD_D02441
Description Rasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Indications and Usage For the treatment of the signs and symptoms of idiopathic Parkinsons disease as initial monotherapy and as adjunct therapy to levodopa.
Marketing Status Not Available
ATC Code N04BD02
DrugBank ID DB01367
KEGG ID D08469
MeSH ID C031967
PubChem ID 3052776
TTD Drug ID D06OMW
NDC Product Code 42291-779; 67877-259; 47781-690; 0093-3061; 67877-260; 42291-780; 47781-683; 42571-220; 16714-771; 16714-770; 0093-3060; 42571-221
Synonyms rasagiline | N-2-propynyl-1-indanamine | AGN 1135 | AGN-1135 | TVP 1022 | TVP1022 | TVP-1022 | N-propargyl-1-aminoindan mesylate | rasagiline hydrochloride | TVP 101 | TVP-101 | 2,3-dihydro-N-2-propynyl-1H-inden-1-amine-(1R)-hydrochloride | Azilect
Chemical Information
Molecular Formula C12H13N
CAS Registry Number 136236-51-6
SMILES C#CCNC1CCC2=CC=CC=C12
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypertension24.08.02.0010.033489%
Hypoaesthesia17.02.06.0230.007442%Not Available
Hypoglycaemia14.06.03.001; 05.06.03.0010.007442%
Hyponatraemia14.05.04.0020.002912%
Hypotension24.06.03.002--
Ileus07.13.01.0010.007442%
Illusion19.10.02.0050.007442%Not Available
Influenza like illness08.01.03.0100.007442%
Inguinal hernia07.16.02.0010.007442%Not Available
Insomnia19.02.01.002; 17.15.03.0020.026047%
Intestinal obstruction07.13.01.0020.007442%Not Available
Loss of consciousness17.02.04.0040.014884%Not Available
Malaise08.01.01.003--
Malignant melanoma23.08.01.001; 16.03.01.0010.011163%Not Available
Memory impairment19.20.01.003; 17.03.02.0030.007442%
Mental impairment19.21.02.003; 17.03.03.0020.007442%Not Available
Movement disorder17.01.02.0100.007442%Not Available
Muscle rigidity17.05.02.005; 15.05.04.0010.007442%Not Available
Muscle spasms15.05.03.0040.011163%
Musculoskeletal pain15.03.04.0070.014884%
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Myocardial ischaemia24.04.04.010; 02.02.02.0080.007442%Not Available
Nausea07.01.07.001--
Neoplasm malignant16.16.01.0010.001941%Not Available
Neurogenic bladder20.03.03.001; 17.10.01.0020.007442%Not Available
Nightmare19.02.03.0030.007442%Not Available
Obsessive-compulsive disorder19.06.05.0020.007442%Not Available
Obsessive-compulsive personality disorder19.05.04.0010.007442%Not Available
On and off phenomenon17.01.05.0040.011163%Not Available
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