Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Enoxaparin
Drug ID BADD_D02438
Description Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies.[L31393] Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients when compared to unfractionated [heparin], without increasing the risk of serious bleeding.[A228178,A228313]
Indications and Usage For the prophylaxis of deep vein thrombosis, which may lead to pulmonary embolism, and also for the prophylaxis of ischemic complications of unstable angina and non-Q-wave myocardial infarction, when concurrently administered with aspirin.
Marketing Status Not Available
ATC Code B01AB01; B01AB12; C05BA03; S01XA14
DrugBank ID DB01225
KEGG ID D07510
MeSH ID D017984
PubChem ID 772
TTD Drug ID Not Available
NDC Product Code Not Available
Synonyms Enoxaparin | Enoxaparine | PK-10,169 | PK 10,169 | PK10,169 | PK-10169 | PK 10169 | PK10169 | EMT-967 | EMT 967 | EMT967 | Lovenox | Clexane | EMT-966 | EMT 966 | EMT966
Chemical Information
Molecular Formula C26H42N2O37S5
CAS Registry Number 9005-49-6
SMILES CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C( C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cardiogenic shock24.06.02.006; 02.05.01.0030.000684%Not Available
Cellulitis23.09.01.001; 11.02.01.0010.004197%Not Available
Cerebral artery occlusion24.04.06.020; 17.08.01.0280.006821%Not Available
Cerebral haemorrhage24.07.04.001; 17.08.01.0030.002464%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest discomfort22.02.08.001; 08.01.08.019; 02.02.02.009--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.0110.007870%Not Available
Chills15.05.03.016; 08.01.09.001--
Cholestasis09.01.01.0010.013642%Not Available
Circulatory collapse24.06.02.0010.001574%Not Available
Coagulation factor decreased13.01.02.0160.001049%Not Available
Coagulation time prolonged13.01.02.0060.001574%Not Available
Coagulopathy01.01.02.0010.002623%Not Available
Coma17.02.09.0010.001369%Not Available
Compartment syndrome24.04.05.006; 15.05.05.0050.003148%Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Coronary artery occlusion24.04.04.013; 02.02.01.0060.001574%Not Available
Cough22.02.03.001--
Cyanosis24.03.01.007; 22.02.02.007; 02.01.02.0020.001049%
Deafness04.02.01.0010.001574%Not Available
Death08.04.01.001--
Dehydration14.05.05.001--
Depressed level of consciousness17.02.04.0020.002623%
Dermatitis allergic23.03.04.003; 10.01.03.0140.002623%Not Available
Dermatitis bullous23.03.01.0020.005247%
Dermatitis exfoliative23.03.07.001; 10.01.01.0040.001049%
Diarrhoea07.02.01.001--
Discomfort08.01.08.0030.002099%Not Available
Disorientation19.13.01.002; 17.02.05.0150.001574%Not Available
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