Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Enoxaparin
Drug ID BADD_D02438
Description Enoxaparin is a common low-molecular-weight heparin (LMWH) used in the prevention and management of various thromboembolic disorders. Initially approved by the FDA in 1993, it is administered by a subcutaneous or intravenous injection and marketed by several pharmaceutical companies.[L31393] Enoxaparin markedly reduces the incidence of venous thromboembolism in hospitalized patients when compared to unfractionated [heparin], without increasing the risk of serious bleeding.[A228178,A228313]
Indications and Usage For the prophylaxis of deep vein thrombosis, which may lead to pulmonary embolism, and also for the prophylaxis of ischemic complications of unstable angina and non-Q-wave myocardial infarction, when concurrently administered with aspirin.
Marketing Status Not Available
ATC Code B01AB01; B01AB12; C05BA03; S01XA14
DrugBank ID DB01225
KEGG ID D07510
MeSH ID D017984
PubChem ID 772
TTD Drug ID Not Available
NDC Product Code Not Available
Synonyms Enoxaparin | Enoxaparine | PK-10,169 | PK 10,169 | PK10,169 | PK-10169 | PK 10169 | PK10169 | EMT-967 | EMT 967 | EMT967 | Lovenox | Clexane | EMT-966 | EMT 966 | EMT966
Chemical Information
Molecular Formula C26H42N2O37S5
CAS Registry Number 9005-49-6
SMILES CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C( C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Drug reaction with eosinophilia and systemic symptoms23.03.05.005; 10.01.01.0210.009444%Not Available
Pneumocystis jirovecii pneumonia22.07.08.009; 11.03.07.0050.000274%Not Available
Multiple organ dysfunction syndrome08.01.03.0570.001232%
Anal incontinence17.05.01.021; 07.01.06.0290.001574%
Abdominal mass07.01.01.0030.000958%Not Available
Antiphospholipid syndrome24.01.01.029; 18.02.04.002; 10.04.01.009; 01.01.02.0160.001049%Not Available
Arterial rupture24.03.02.027; 12.01.11.0100.001049%Not Available
Blood blister23.03.01.028; 12.01.06.0130.001574%Not Available
Computerised tomogram abnormal13.18.03.0020.001049%Not Available
Dermatitis exfoliative generalised10.01.01.029; 23.03.07.0020.001049%Not Available
Foetal malnutrition18.03.01.0040.001049%Not Available
Hemianopia homonymous17.17.01.024; 06.02.07.0070.001049%Not Available
Nephritis allergic20.05.01.018; 10.01.03.0440.000274%Not Available
Placenta praevia18.05.02.0040.001574%Not Available
Renal haematoma20.01.02.018; 24.07.07.004; 12.01.05.0060.000274%Not Available
Small for dates baby18.04.02.0020.004197%Not Available
Live birth18.08.02.0070.001049%Not Available
Heparin-induced thrombocytopenia test13.01.04.0130.001049%Not Available
Factor V Leiden mutation01.01.02.019; 03.15.01.0080.001049%Not Available
Intracranial haematoma24.07.04.027; 17.08.01.0510.000274%Not Available
Anticoagulation drug level below therapeutic13.17.01.0190.001049%Not Available
Arterial haemorrhage24.07.01.0630.000274%Not Available
Pelvic fluid collection21.07.04.011; 07.07.01.0090.001049%Not Available
Abdominal wall haematoma24.07.02.039; 07.16.05.0050.017314%Not Available
Skin plaque23.03.03.0440.001049%Not Available
Coma scale abnormal13.07.03.0120.001049%Not Available
Inflammatory marker increased13.09.02.0030.001049%Not Available
Foetal placental thrombosis18.05.02.002; 24.01.05.0090.001049%Not Available
Nonreassuring foetal heart rate pattern18.03.02.017; 02.03.02.0270.004197%Not Available
Chest wall haematoma24.07.01.065; 15.03.01.0230.001049%Not Available
The 15th Page    First    Pre   15 16    Next   Last    Total 16 Pages