Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Diclofenamide
Drug ID BADD_D02437
Description A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Indications and Usage For adjunctive treatment of: chronic simple (open-angle) glaucoma, secondary glaucoma, and preoperatively in acute angle-closure glaucoma where delay of surgery is desired in order to lower intraocular pressure
Marketing Status Not Available
ATC Code S01EC02
DrugBank ID DB01144
KEGG ID D00518
MeSH ID Not Available
PubChem ID 3038
TTD Drug ID D0J4GO
NDC Product Code Not Available
Synonyms Not Available
Chemical Information
Molecular Formula C6H6Cl2N2O4S2
CAS Registry Number 120-97-8
SMILES C1=C(C=C(C(=C1S(=O)(=O)N)Cl)Cl)S(=O)(=O)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.002296%Not Available
Abdominal distension07.01.04.0010.000417%
Abdominal pain07.01.05.0020.000835%
Abdominal pain upper07.01.05.0030.001044%
Acidosis14.01.03.0020.000417%
Alopecia23.02.02.001--
Amnesia17.03.02.001; 19.20.01.0010.001044%
Anxiety19.06.02.0020.001461%
Aphasia19.21.01.001; 17.02.03.0010.001461%
Arthralgia15.01.02.0010.002505%
Asthenia08.01.01.0010.006471%Not Available
Back pain15.03.04.0050.001044%
Blood calcium decreased13.11.01.0020.000417%Not Available
Blood glucose increased13.02.02.0020.000626%Not Available
Blood iron decreased13.11.01.0060.000417%Not Available
Blood potassium decreased13.11.01.0100.004383%Not Available
Blood potassium increased13.11.01.0110.000417%Not Available
Blood pressure decreased13.14.03.0020.000417%Not Available
Bronchitis22.07.01.001; 11.01.09.0010.000417%
Burning sensation17.02.06.001; 08.01.09.0290.001879%Not Available
Chest discomfort22.02.08.001; 08.01.08.019; 02.02.02.0090.000626%Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.0110.000626%Not Available
Chills08.01.09.001; 15.05.03.0160.000626%
Confusional state19.13.01.001; 17.02.03.0050.008767%
Constipation07.02.02.001--
Cough22.02.03.0010.001044%
Dehydration14.05.05.0010.000835%
Depressed mood19.15.02.0010.000626%Not Available
Depression19.15.01.0010.001252%
Diarrhoea07.02.01.0010.003966%
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