Drug Name |
Verapamil |
Drug ID |
BADD_D02348 |
Description |
Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced into therapy in the early 1960s.[A188514] It is a member of the non-dihydropyridine class of calcium channel blockers, which includes drugs like [diltiazem] and [flunarizine], but is chemically unrelated to other cardioactive medications.[L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer, each of which is pharmacologically distinct - the S-enantiomer carries approximately 20-fold greater potency than the R-enantiomer, but is metabolized at a higher rate.[A188435] |
Indications and Usage |
For the treatment of hypertension, angina, and cluster headache prophylaxis. |
Marketing Status |
Prescription; Discontinued |
ATC Code |
C08DA01 |
DrugBank ID |
DB00661
|
KEGG ID |
D02356
|
MeSH ID |
D014700
|
PubChem ID |
2520
|
TTD Drug ID |
D0R0FE
|
NDC Product Code |
70966-0029 |
Synonyms |
Verapamil | Iproveratril | Cordilox | Dexverapamil | Verapamil Hydrochloride | Hydrochloride, Verapamil | Finoptin | Izoptin | Isoptine | Isoptin | Lekoptin | Calan | Falicard |