| Pharmaceutical Information |
| Drug Name |
Valrubicin |
| Drug ID |
BADD_D02330 |
| Description |
Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR. It is a semisynthetic analog of the [doxorubicin], which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder. |
| Indications and Usage |
For the treatment of cancer of the bladder. |
| Marketing Status |
Prescription |
| ATC Code |
L01DB09 |
| DrugBank ID |
DB00385
|
| KEGG ID |
D02697
|
| MeSH ID |
C016163
|
| PubChem ID |
454216
|
| TTD Drug ID |
D07IPB
|
| NDC Product Code |
27831-005; 67979-001; 72027-005; 77391-005 |
| Synonyms |
valrubicin | N-trifluoroacetyladriamycin 14-valerate | Valtaxin | Valstar | AD 32 | AD-32 | NSC-246131 |
|
| Chemical Information |
| Molecular Formula |
C34H36F3NO13 |
| CAS Registry Number |
56124-62-0 |
| SMILES |
CCCCC(=O)OCC(=O)C1(CC(C2=C(C1)C(=C3C(=C2O)C(=O)C4=C(C3=O)C=CC=C4OC)O)OC5CC(C(C(O
5)C)O)NC(=O)C(F)(F)F)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Bladder cancer recurrent | 20.03.04.005; 16.08.01.003 | 0.000533% | | Not Available |
|
|
|
