Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Valrubicin
Drug ID BADD_D02330
Description Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR. It is a semisynthetic analog of the [doxorubicin], which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder.
Indications and Usage For the treatment of cancer of the bladder.
Marketing Status Prescription
ATC Code L01DB09
DrugBank ID DB00385
KEGG ID D02697
MeSH ID C016163
PubChem ID 454216
TTD Drug ID D07IPB
NDC Product Code 27831-005; 67979-001; 72027-005; 77391-005
Synonyms valrubicin | N-trifluoroacetyladriamycin 14-valerate | Valtaxin | Valstar | AD 32 | AD-32 | NSC-246131
Chemical Information
Molecular Formula C34H36F3NO13
CAS Registry Number 56124-62-0
SMILES CCCCC(=O)OCC(=O)C1(CC(C2=C(C1)C(=C3C(=C2O)C(=O)C4=C(C3=O)C=CC=C4OC)O)OC5CC(C(C(O 5)C)O)NC(=O)C(F)(F)F)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.001066%
Ageusia17.02.07.001; 07.14.03.003--Not Available
Anaemia01.03.02.001--
Asthenia08.01.01.0010.000533%Not Available
Back pain15.03.04.005--
Bladder pain20.02.02.001--Not Available
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Chest pain08.01.08.002; 02.02.02.011; 22.02.08.003--Not Available
Cystitis20.03.02.002; 11.01.14.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness17.02.05.003; 02.01.02.004; 24.06.02.007--
Dysuria20.02.02.0020.000533%
Feeling abnormal08.01.09.014--Not Available
Feeling hot08.01.09.0090.001332%Not Available
Flatulence07.01.04.002--
Frequent bowel movements07.02.04.0020.000533%Not Available
Gastrointestinal pain07.01.05.005--
Haematuria24.07.01.047; 20.02.01.006--
Headache17.14.01.001--
Hyperglycaemia14.06.02.002; 05.06.02.002--
Infection11.01.08.0020.000208%Not Available
Irritability19.04.02.013; 08.01.03.011--
Local reaction08.01.03.012--Not Available
Malaise08.01.01.003--
Micturition urgency20.02.02.006--
Myalgia15.05.02.001--
Nausea07.01.07.001--
The 1th Page    1 2 3    Next   Last    Total 3 Pages