Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ursodiol
Drug ID BADD_D02321
Description Ursodeoxycholic acid is an epimer of [chenodeoxycholic acid]. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.
Indications and Usage The drug reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery.
Marketing Status Prescription; Discontinued
ATC Code A05AA02
DrugBank ID DB01586
KEGG ID D00734
MeSH ID D014580
PubChem ID 31401
TTD Drug ID D0G3SH
NDC Product Code 70771-1407; 42806-503; 68462-474; 0591-3159; 46438-0090; 60592-998; 72887-144; 80056-144; 62991-2185; 72789-205; 72664-217; 70771-1524; 55154-3355; 70710-1127; 42385-946; 51552-0906; 63629-2287; 0904-7168; 64380-918; 51927-2909; 80056-143; 22365-012; 63629-8353; 24658-780; 49884-413; 63629-2286; 63629-1048; 51079-383; 64380-919; 70771-1408; 0395-8174; 64980-483; 60687-100; 66039-936; 49884-412; 38779-1987; 69238-1540; 68462-473; 0904-6221; 24658-999; 49452-8085; 58914-790; 63629-1173; 52544-930; 68001-377; 46438-0654; 49345-2612; 64380-844; 0378-1730; 72887-143; 68001-378; 61200-001; 60429-662; 70710-1483; 70710-1128; 50268-797; 0527-1326; 60687-527; 0591-3005; 0591-2998; 46438-0089; 51224-151; 0904-6890; 72969-076; 71930-015; 58914-785; 46438-0653
Synonyms Ursodeoxycholic Acid | Acid, Ursodeoxycholic | Ursacholic Acid | Acid, Ursacholic | 3 alpha,7 beta-Dihydroxy-5 beta-cholan-24-oic Acid | 3 alpha,7 beta Dihydroxy 5 beta cholan 24 oic Acid | Ursodiol | Deoxyursocholic Acid | Acid, Deoxyursocholic | Ursolvan | Delursan | Destolit | Sodium Ursodeoxycholate | Ursodeoxycholate, Sodium | Urdox | Urso | Urso Heumann | Ursobilane | Ursochol | Ursofalk | Ursogal | Ursolite | Cholit-Ursan | Cholofalk
Chemical Information
Molecular Formula C24H40O4
CAS Registry Number 128-13-2
SMILES CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Neck pain15.03.04.009--
Neoplasm16.16.02.001--Not Available
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.003--Not Available
Nocturia20.02.03.001--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Oesophagitis07.08.05.001--
Orthostatic hypotension24.06.03.004; 17.05.01.020--Not Available
Otitis media11.01.05.004; 04.05.01.001--
Pain08.01.08.004--
Palpitations02.01.02.003--
Pancreatitis07.18.01.001--
Paraesthesia17.02.06.005--
Peptic ulcer07.04.07.001--Not Available
Pericardial effusion02.06.01.002--
Pericarditis02.06.02.001--
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Photosensitivity reaction23.03.09.003--
Pleural effusion22.05.02.002--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pollakiuria20.02.02.007--
Pruritus23.03.12.001--
Psoriasis23.03.14.002; 10.02.01.036--Not Available
Pulmonary fibrosis22.01.02.006--
Pulmonary hypertension24.08.03.002; 22.06.01.001--
Rash23.03.13.001--Not Available
Renal failure20.01.03.005--Not Available
Retinal disorder06.08.03.005--Not Available
Rhinitis22.07.03.006; 11.01.13.004--
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