Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ursodiol
Drug ID BADD_D02321
Description Ursodeoxycholic acid is an epimer of [chenodeoxycholic acid]. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.
Indications and Usage The drug reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery.
Marketing Status Prescription; Discontinued
ATC Code A05AA02
DrugBank ID DB01586
KEGG ID D00734
MeSH ID D014580
PubChem ID 31401
TTD Drug ID D0G3SH
NDC Product Code 70771-1407; 42806-503; 68462-474; 0591-3159; 46438-0090; 60592-998; 72887-144; 80056-144; 62991-2185; 72789-205; 72664-217; 70771-1524; 55154-3355; 70710-1127; 42385-946; 51552-0906; 63629-2287; 0904-7168; 64380-918; 51927-2909; 80056-143; 22365-012; 63629-8353; 24658-780; 49884-413; 63629-2286; 63629-1048; 51079-383; 64380-919; 70771-1408; 0395-8174; 64980-483; 60687-100; 66039-936; 49884-412; 38779-1987; 69238-1540; 68462-473; 0904-6221; 24658-999; 49452-8085; 58914-790; 63629-1173; 52544-930; 68001-377; 46438-0654; 49345-2612; 64380-844; 0378-1730; 72887-143; 68001-378; 61200-001; 60429-662; 70710-1483; 70710-1128; 50268-797; 0527-1326; 60687-527; 0591-3005; 0591-2998; 46438-0089; 51224-151; 0904-6890; 72969-076; 71930-015; 58914-785; 46438-0653
Synonyms Ursodeoxycholic Acid | Acid, Ursodeoxycholic | Ursacholic Acid | Acid, Ursacholic | 3 alpha,7 beta-Dihydroxy-5 beta-cholan-24-oic Acid | 3 alpha,7 beta Dihydroxy 5 beta cholan 24 oic Acid | Ursodiol | Deoxyursocholic Acid | Acid, Deoxyursocholic | Ursolvan | Delursan | Destolit | Sodium Ursodeoxycholate | Ursodeoxycholate, Sodium | Urdox | Urso | Urso Heumann | Ursobilane | Ursochol | Ursofalk | Ursogal | Ursolite | Cholit-Ursan | Cholofalk
Chemical Information
Molecular Formula C24H40O4
CAS Registry Number 128-13-2
SMILES CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Acne23.02.01.001--Not Available
Alanine aminotransferase increased13.03.01.003--
Alopecia23.02.02.001--
Amblyopia06.02.01.001--Not Available
Amnesia17.03.02.001; 19.20.01.001--
Amyloidosis10.02.05.001--Not Available
Anaemia01.03.02.001--
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Aspartate aminotransferase increased13.03.01.006--
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Atrial fibrillation02.03.03.002--
Atrioventricular block complete02.03.01.003--
Back pain15.03.04.005--
Bladder pain20.02.02.001--Not Available
Blood bilirubin increased13.03.01.008--
Blood creatinine increased13.13.01.004--
Blood glucose increased13.02.02.002--Not Available
Body temperature increased13.15.01.001--Not Available
Bone disorder15.02.04.004--Not Available
Bone pain15.02.01.001--
Breast neoplasm21.05.01.004; 16.10.02.001--Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Cardiac failure02.05.01.001--
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