| Pharmaceutical Information |
| Drug Name |
Trospium |
| Drug ID |
BADD_D02305 |
| Description |
Trospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably.[L6208] An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination.[L6208] Trospium is manufactured by _Indevus Pharmaceutical Inc._ and was granted FDA approval in 2007.[L6211] |
| Indications and Usage |
For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency, detrusor instability and frequency of micturition. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
G04BD09 |
| DrugBank ID |
DB00209
|
| KEGG ID |
D01103
|
| MeSH ID |
C003330
|
| PubChem ID |
5284632
|
| TTD Drug ID |
D05TIB
|
| NDC Product Code |
Not Available |
| Synonyms |
trospium chloride | azoniaspiro compound XVII | azoniaspiro(3 alpha-benziloyloxynortropane-8,1'- pyrrolidine) chloride | Spasmex | Uraton | Spasmolyt | Spasmo-Urgenin TC | Spasmo-lyt | Spasmo-Rhoival TC | Trospi | Ceris | Uraplex | Spasmo-Urgenin |
|
| Chemical Information |
| Molecular Formula |
C25H30NO3+ |
| CAS Registry Number |
47608-32-2 |
| SMILES |
C1CC[N+]2(C1)C3CCC2CC(C3)OC(=O)C(C4=CC=CC=C4)(C5=CC=CC=C5)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Vulvovaginal pain | 21.08.02.009 | - | - | |
|
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|
