Drug Name |
Trihexyphenidyl hydrochloride |
Drug ID |
BADD_D02285 |
Description |
Trihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced extrapyramidal disorders.[L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity.[A229103] Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment due to significant adverse effects.[L31843] It has largely been replaced by drugs such as [levodopa].[L31843]
Trihexyphenidyl was granted FDA approval on 13 May 1949.[L31768] |
Indications and Usage |
Indicated for the treatment of parkinson's disease and extrapyramidal reactions caused by drugs. |
Marketing Status |
Prescription; Discontinued |
ATC Code |
N04AA01 |
DrugBank ID |
DB00376
|
KEGG ID |
D00787
|
MeSH ID |
D014282
|
PubChem ID |
66007
|
TTD Drug ID |
D09GFL
|
NDC Product Code |
17337-0038; 51407-265; 70954-211; 0591-5335; 0121-0658; 70518-1140; 16571-160; 70518-1612; 70518-2878; 69452-241; 70518-1657; 69452-242; 58159-064; 0591-5337; 50090-5205; 70518-1021; 70954-212; 63850-0021; 50090-2994; 63850-0022; 70518-3288; 16571-161; 70518-2409; 70518-2410; 71554-022; 70518-2880; 70518-3268; 51407-266 |
Synonyms |
Trihexyphenidyl | Benzhexol | Artane | Cyclodol | Hipokinon | Trihexyphenidyl Hydrochloride Elixir | Parkopan | Trihexane | Trihexidyl Hydrochloride | Trihexyphenidyl Hydrochloride | Apo-Trihex | Apo Trihex | ApoTrihex | Parkinane |