| Pharmaceutical Information |
| Drug Name |
Trihexyphenidyl |
| Drug ID |
BADD_D02284 |
| Description |
Trihexyphenidyl is a centrally acting muscarinic antagonist used for treatment of parkinsonism and drug-induced extrapyramidal disorders.[L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity.[A229103] Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment due to significant adverse effects.[L31843] It has largely been replaced by drugs such as [levodopa].[L31843]
Trihexyphenidyl was granted FDA approval on 13 May 1949.[L31768] |
| Indications and Usage |
Indicated for the treatment of parkinson's disease and extrapyramidal reactions caused by drugs. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
N04AA01 |
| DrugBank ID |
DB00376
|
| KEGG ID |
D08638
|
| MeSH ID |
D014282
|
| PubChem ID |
5572
|
| TTD Drug ID |
D09GFL
|
| NDC Product Code |
63850-6535 |
| Synonyms |
Trihexyphenidyl | Benzhexol | Artane | Cyclodol | Hipokinon | Trihexyphenidyl Hydrochloride Elixir | Parkopan | Trihexane | Trihexidyl Hydrochloride | Trihexyphenidyl Hydrochloride | Apo-Trihex | Apo Trihex | ApoTrihex | Parkinane |
|
| Chemical Information |
| Molecular Formula |
C20H31NO |
| CAS Registry Number |
144-11-6 |
| SMILES |
C1CCC(CC1)C(CCN2CCCCC2)(C3=CC=CC=C3)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
|
