Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Triamcinolone acetonide
Drug ID BADD_D02272
Description Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis.[L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses.[L8249] Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate.[L8246,L8249,L8252,L8255,L8258,L8261,L8264] Triamcinolone was granted FDA approval on 3 December 1957.[L8243] In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval[L38973] - for the treatment of patients with macular edema associated with uveitis.[L38963]
Indications and Usage For the treatment of perennial and seasonal allergic rhinitis.
Marketing Status Prescription; OTC; Discontinued
ATC Code A01AC01; C05AA12; D07AB09; D07XB02; H02AB08; R01AD11; R03BA06; S01BA05
DrugBank ID DB00620
KEGG ID D00983
MeSH ID D014222
PubChem ID 6436
TTD Drug ID Not Available
NDC Product Code 72189-277; 53002-9121; 0713-0676; 72603-108; 0065-0543; 49999-150; 62011-0320; 76420-162; 44118-711; 63629-8783; 68788-7814; 63187-214; 63629-8782; 70518-3373; 16714-150; 70121-1168; 41250-443; 68788-0149; 70121-1657; 68071-4168; 68071-2339; 41520-443; 63629-8708; 50090-1444; 33342-333; 68462-131; 68071-4397; 0713-0229; 59779-746; 22552-0032; 70121-1655; 70121-1651; 68071-2464; 16714-130; 70121-1652; 50090-2360; 68071-4630; 70518-1094; 67438-045; 0713-0225; 46439-8742; 71205-451; 71205-108; 63629-8778; 33342-331; 70518-0075; 12516-1510; 71565-040; 68071-4286; 52128-173; 0003-0293; 0703-0241; 0168-0003; 0168-0004; 51672-1284; 60432-560; 0703-0243; 68071-1623; 76420-085; 11822-0443; 0003-0494; 0703-0245; 63629-8456; 0168-0005; 49076-6701; 0713-0679; 49035-443; 68071-5070; 52565-011; 45802-045; 71205-124; 71161-135; 41167-5800; 63629-8785; 71205-627; 0316-0175; 71205-009; 66267-934; 35573-404; 70121-1049; 68788-7797; 45802-065; 53002-0150; 76420-220; 50090-4106; 68462-798; 71205-033; 76420-222; 45802-063; 51552-0033; 68071-4564; 24208-040; 21130-443; 12516-1509; 82298-123; 0713-0655; 45802-055; 71205-038; 41167-5900; 64380-871; 67877-317; 16714-140; 72189-039; 37808-443; 50090-2658; 52945-068; 50090-0819; 63187-025; 0003-0315; 50090-0295; 12516-1508; 50090-0162; 63629-8780; 0316-0165; 63629-8779; 0713-0228; 36800-621; 55910-280; 70518-2403; 33342-332; 74157-901; 68071-2516; 72603-202; 68071-2294; 11673-717; 63629-8781; 0363-0811; 60722-3012; 0316-0170; 64380-870; 45802-109; 0168-0002; 33342-328; 67877-251; 66267-933; 68788-7048; 51672-1335; 0168-0006; 70752-130; 0113-0443; 69842-244; 63187-495; 53002-9130; 59088-733; 61919-650; 63629-2407; 70121-1169; 68071-2362; 52565-010; 53002-9330; 63187-661; 45802-049; 67877-318; 46122-385; 76003-1145; 50090-3522; 72603-401; 10631-093; 0113-7005; 30142-443; 52565-056; 76420-203; 52817-811; 63629-8841; 68071-4391; 50090-2542; 68788-7501; 50090-0293; 68788-9172; 46287-010; 53002-0151; 70529-048; 63981-443; 50090-3802; 45802-064; 70121-1654; 33342-329; 45802-817; 50090-0256; 46439-8730; 45802-054; 63629-8707; 53002-9120; 33342-327; 63629-2406; 51927-0134; 64980-320; 70518-2393; 65089-0008; 68071-1803; 51672-1282; 49452-7900; 50090-0362; 52565-014; 0713-0226; 38779-0011; 70121-1653; 68788-7506; 68462-797; 57582-018; 51672-1267; 42571-385; 63187-870; 61919-594; 69256-443; 53002-9333; 59088-843; 50090-3754; 70000-0204; 53002-9334; 62991-1156; 70752-129; 46439-8703; 72288-443; 68071-2361; 70518-2285; 61919-619; 68071-1872; 30142-813; 70518-2938; 24470-922; 68071-4383; 52565-048; 45865-898; 60432-561; 49999-216; 53002-9331; 64980-429; 63275-9943; 70518-2963; 53002-9770; 64380-901; 41163-443; 40032-097; 51862-290; 0713-0766; 68071-4561; 63187-053
Synonyms Triamcinolone Acetonide | Acetonide, Triamcinolone | Cinonide | Tricort-40 | Tricort 40 | Tricort40 | Kenalog | Kenalog 40 | Azmacort | Kenacort A
Chemical Information
Molecular Formula C24H31FO6
CAS Registry Number 76-25-5
SMILES CC1(OC2CC3C4CCC5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Miliaria23.02.03.014--Not Available
Monoplegia17.01.04.003--Not Available
Mood swings19.04.03.001--Not Available
Multiple fractures12.04.02.009; 15.08.02.005--Not Available
Muscle disorder15.05.03.014--Not Available
Muscular weakness17.05.03.005; 15.05.06.001--
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Myocardial rupture02.04.02.002; 12.01.11.002--Not Available
Myopathy15.05.05.001--Not Available
Nasal congestion22.04.04.001--
Nasal septum perforation22.04.03.003--Not Available
Nasopharyngitis11.01.13.002; 22.07.03.002--Not Available
Nausea07.01.07.001--
Neuritis17.09.03.001--Not Available
Neuropathic arthropathy15.01.01.007; 17.09.03.008--Not Available
Neuropathy peripheral17.09.03.003--Not Available
Nitrogen balance negative13.13.01.010--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Oesophageal candidiasis11.03.03.008; 07.19.06.001--Not Available
Oesophagitis07.08.05.001--
Opportunistic infection11.01.08.007--Not Available
Optic neuritis17.04.05.001; 10.04.10.002; 06.04.08.002--Not Available
Oral candidiasis11.03.03.004; 07.05.07.001--Not Available
Osteoarthritis15.01.04.001--Not Available
Osteonecrosis15.02.04.007; 24.04.05.004--
Osteoporosis15.02.03.002; 14.04.04.002--
Otitis media11.01.05.004; 04.05.01.001--
Pain08.01.08.004--
Pancreatitis07.18.01.001--
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