| Drug Name |
Travoprost |
| Drug ID |
BADD_D02265 |
| Description |
Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure [FDA Label]. It is a synthetic prostaglandin F2alpha analog [FDA Label]. Having been a well-received therapeutic agent with demonstrated efficacy and safety, travoprost is currently approved by the US FDA as a first-line treatment for lowering intraocular pressure in patients with open-angle glaucoma or ocular hypotension [L5155]. Furthermore, this approval also solidifies the medication as the first and only prostaglandin analog approved by the FDA for first-line treatment of glaucoma patients that does not contain the preservative benzalkonium chloride [L5155]. Moreover, travoprost is also currently approved in the EU for the decrease of elevated intraocular pressure in paediatric patients aged 2 months to < 18 years with ocular hypertension or paediatric glaucoma [L5146, L5152]. |
| Indications and Usage |
Ophthalmic solution used for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications or insufficiently responsive (failed to achieve target IOP determined after multiple measurements over time) to another intraocular pressure lowering medication. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
S01EE04 |
| DrugBank ID |
DB00287
|
| KEGG ID |
D01964
|
| MeSH ID |
D000069557
|
| PubChem ID |
5282226
|
| TTD Drug ID |
D09CZA
|
| NDC Product Code |
54893-0020; 40016-006; 0078-0946; 82231-114; 45542-1162; 38779-3063; 64181-0028; 63629-8839; 65035-131; 65129-1207; 61556-040; 0781-6185; 24002-0022; 68245-0003; 63190-0350; 60505-0593; 63629-8840; 55359-540 |
| Synonyms |
Travoprost | Travatan Z | Z, Travatan | Travatan | (((1R)-(1alpha(Z),2beta(1E,3R*),3alpha,5alpha))-7-(3,5-dihydroxy-2-(3-hydroxy-4-(3-trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-5-heptenoic acid, 1-methylethyl ester | AL-6221 | AL 6221 | AL6221 |
