| Pharmaceutical Information |
| Drug Name |
Tranylcypromine sulfate |
| Drug ID |
BADD_D02263 |
| Description |
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311).
Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine). |
| Indications and Usage |
For the treatment of major depressive episode without melancholia. |
| Marketing Status |
Prescription |
| ATC Code |
N06AF04 |
| DrugBank ID |
DB00752
|
| KEGG ID |
D00826
|
| MeSH ID |
D014191
|
| PubChem ID |
25267092
|
| TTD Drug ID |
D0H0HJ
|
| NDC Product Code |
59212-447; 49884-032; 0591-5590; 64330-090; 58159-082; 64380-176; 63629-2247; 46204-0130; 60429-210 |
| Synonyms |
Tranylcypromine | trans-2-Phenylcyclopropylamine | trans 2 Phenylcyclopropylamine | Tranylcypromine Sulfate | Sulfate, Tranylcypromine | Jatrosom | Transamine | Parnate |
|
| Chemical Information |
| Molecular Formula |
C18H24N2O4S |
| CAS Registry Number |
13492-01-8 |
| SMILES |
C1C(C1N)C2=CC=CC=C2.C1C(C1N)C2=CC=CC=C2.OS(=O)(=O)O |
| Chemical Structure |
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|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Metabolic disorder | Activity-regulated cytoskeleton-associated protein | Q9WV31 | Not Available | Not Available |
|
| ADRs Induced by Drug |
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|
