Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Trandolaprilat
Drug ID BADD_D02260
Description The active metabolite of the prodrug [Trandolapril].
Indications and Usage Not Available
Marketing Status experimental
ATC Code Not Available
DrugBank ID DB14209
KEGG ID Not Available
MeSH ID C061095
PubChem ID 5464097
TTD Drug ID Not Available
NDC Product Code Not Available
UNII RR6866VL0O
Synonyms trandolaprilat | 1-(2-((1-carboxy-3-phenylpropyl)amino)-1-oxopropyl)octahydro-1H-indole-2-carboxylic acid | trandolaprilate | RU 44 403 | RU-44403 | RU 44403 | trandolaprilat, (2S-(1R*(R*)),2alpha,3aalpha,7abeta)-isomer | trandolaprilat, (2S-(1(R*(R*)),2alpha,3abeta,7abeta))-isomer | trandolaprilat, (2S-(1(S*(R*)),2alpha,3aalpha,7abeta))-isomer
Chemical Information
Molecular Formula C22H30N2O5
CAS Registry Number 87679-71-8
SMILES CC(C(=O)N1C2CCCCC2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Angina pectoris24.04.04.002; 02.02.02.002--
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.001--Not Available
Atrioventricular block first degree02.03.01.004--
Blood creatinine increased13.13.01.004--
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Cardiac failure02.05.01.001--
Cardiogenic shock02.05.01.003; 24.06.02.006--Not Available
Cerebral haemorrhage24.07.04.001; 17.08.01.003--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Constipation07.02.02.001--
Cough22.02.03.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dry mouth07.06.01.002--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Epistaxis24.07.01.005; 22.04.03.001--
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