Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Tolterodine tartrate
Drug ID BADD_D02245
Description Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Indications and Usage For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).
Marketing Status Prescription; Discontinued
ATC Code G04BD07
DrugBank ID DB01036
KEGG ID D01148
MeSH ID D000068737
PubChem ID 9847786
TTD Drug ID D0BZ7W
NDC Product Code 31722-608; 10135-707; 53104-7572; 65862-394; 0093-7164; 52286-0018; 73152-026; 31722-805; 53747-035; 70436-160; 64552-4002; 59762-0048; 50370-0023; 0009-5190; 11014-0374; 29300-240; 65977-0029; 11014-0122; 43975-322; 49706-1835; 43975-323; 33342-098; 59762-0800; 10135-706; 0009-0420; 55289-132; 0093-7163; 11014-0123; 59762-0047; 0093-0018; 70518-2794; 16571-126; 0009-4544; 50090-3475; 55111-855; 70436-161; 14593-901; 71205-319; 59762-0170; 27241-191; 33342-097; 70518-1416; 31722-806; 31722-607; 27241-192; 71666-009; 16571-127; 0009-4541; 0093-0010; 29300-239; 65427-020; 0009-5191
Synonyms Tolterodine Tartrate | Tartrate, Tolterodine | Tolterodine | Detrol | Detrol LA | Urotrol | PHA-686464B | PHA 686464B | PHA686464B | Detrusitol | Unidet
Chemical Information
Molecular Formula C26H37NO7
CAS Registry Number 124937-52-6
SMILES CC1=CC(=C(C=C1)O)C(CCN(C(C)C)C(C)C)C2=CC=CC=C2.C(C(C(=O)O)O)(C(=O)O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Palpitations02.01.02.003--
Sinusitis22.07.03.007; 11.01.13.005--
Somnolence19.02.05.003; 17.02.04.006--
Tachycardia02.03.02.007--Not Available
Urinary retention20.02.02.011--
Vertigo04.04.01.003; 17.02.12.002--
Visual impairment06.02.06.008--Not Available
Weight increased13.15.01.006--
Xerophthalmia14.12.03.002; 06.06.03.008--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
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