Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Tolterodine
Drug ID BADD_D02244
Description Tolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Indications and Usage For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).
Marketing Status Prescription; Discontinued
ATC Code G04BD07
DrugBank ID DB01036
KEGG ID D00646
MeSH ID D000068737
PubChem ID 443879
TTD Drug ID D0BZ7W
NDC Product Code 65427-022; 0904-6593; 60687-330; 13668-190; 13668-189; 0904-6592; 60687-319
Synonyms Tolterodine Tartrate | Tartrate, Tolterodine | Tolterodine | Detrol | Detrol LA | Urotrol | PHA-686464B | PHA 686464B | PHA686464B | Detrusitol | Unidet
Chemical Information
Molecular Formula C22H31NO
CAS Registry Number 124937-51-5
SMILES CC1=CC(=C(C=C1)O)C(CCN(C(C)C)C(C)C)C2=CC=CC=C2
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Visual acuity reduced06.02.03.001; 17.17.01.0110.002055%
Visual impairment06.02.06.0080.001541%Not Available
Vomiting07.01.07.0030.002569%
Weight increased13.15.01.006--
Xerophthalmia14.12.03.002; 06.06.03.008--Not Available
Balance disorder17.02.02.0070.001028%Not Available
Body height decreased13.15.01.0290.001028%Not Available
Bladder disorder20.03.01.0020.001028%Not Available
Drug intolerance08.06.01.0130.002569%Not Available
Renal impairment20.01.03.0100.001028%Not Available
Treatment failure08.06.01.0170.000268%Not Available
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