Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Testolactone
Drug ID BADD_D02169
Description An antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
Indications and Usage For palliative treatment of advanced breast cancer in postmenopausal women.
Marketing Status Discontinued
ATC Code Not Available
DrugBank ID DB00894
KEGG ID D00153
MeSH ID D013738
PubChem ID 13769
TTD Drug ID D0C7JF
NDC Product Code Not Available
Synonyms Testolactone | 1-Dehydrotestolactone | 1 Dehydrotestolactone | delta(1)-Testolactone | Teslac
Chemical Information
Molecular Formula C19H24O3
CAS Registry Number 968-93-4
SMILES CC12CCC3C(C1CCC(=O)O2)CCC4=CC(=O)C=CC34C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Alopecia23.02.02.001--
Blood pressure increased13.14.03.005--Not Available
Discomfort08.01.08.003--Not Available
Erythema23.03.06.001--Not Available
Feeling abnormal08.01.09.014--Not Available
Glossitis07.14.01.001--Not Available
Malaise08.01.01.003--
Nausea07.01.07.001--
Oedema14.05.06.010; 08.01.07.006--Not Available
Pain08.01.08.004--
Paraesthesia17.02.06.005--
Vomiting07.01.07.003--
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049--Not Available
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