Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Teriparatide
Drug ID BADD_D02166
Description Teriparatide (recombinant human parathyroid hormone) is a potent anabolic agent used in the treatment of osteoporosis. It is manufactured and marketed by Eli Lilly and Company.
Indications and Usage For the treatment of osteoporosis in men and postmenopausal women who are at high risk for having a fracture. Also used to increase bone mass in men with primary or hypogonadal osteoporosis who are at high risk for fracture.
Marketing Status Discontinued; Prescription
ATC Code H05AA02
DrugBank ID DB06285
KEGG ID D06078
MeSH ID D019379
PubChem ID 16133850
TTD Drug ID D0YA2L
NDC Product Code 63557-0021; 69766-088; 32861-0008; 68594-030; 47781-652; 0002-8400; 52221-119; 41524-0010; 65129-1312
Synonyms Teriparatide | hPTH (1-34) | Human Parathyroid Hormone (1-34) | Parathar | Teriparatide Acetate | Forteo
Chemical Information
Molecular Formula C181H291N55O51S2
CAS Registry Number 52232-67-4
SMILES CCC(C)C(C(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(CC1=CNC=N1)C(=O)NC( CC(=O)N)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC2=CNC=N2)C(=O)NC(CC(C)C)C( =O)NC(CC(=O)N)C(=O)NC(CO)C(=O)NC(CCSC)C(=O)NC(CCC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)N C(C(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC(C)C)C(=O)NC(CCCNC (=N)N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O) O)C(=O)NC(C(C)C)C(=O)NC(CC5=CNC=N5)C(=O)NC(CC(=O)N)C(=O)NC(CC6=CC=CC=C6)C(=O)O)N C(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)C)NC(=O)C(CO)N
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaemia01.03.02.001--
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Blood calcium increased13.11.01.003--Not Available
Blood uric acid increased13.02.04.001--Not Available
Bone disorder15.02.04.004--Not Available
Bone neoplasm16.29.01.001; 15.09.02.001--Not Available
Calculus urinary20.04.02.001--Not Available
Cardiac murmur13.14.01.001--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Constipation07.02.02.001--
Cough22.02.03.001--
Death08.04.01.001--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness24.06.02.007; 02.01.02.004; 17.02.05.003--
Drug hypersensitivity10.01.01.001--Not Available
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Ear disorder04.03.01.001--Not Available
Emphysema22.01.02.002--Not Available
Erythema23.03.06.001--Not Available
Face oedema10.01.05.002; 08.01.07.003; 23.04.01.004--
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