Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Spinosad
Drug ID BADD_D02065
Description Spinosad is a pediculicide mixture of spinosyn A and spinosyn D (in an approximately 5:1 ratio, respectively) used in the topical treatment of head lice in children (four years old and older) and in adults. Spinosad is an insecticide based on a compound found in S. spinosa, a bacterial species. Spinosad has also been experimented for use in cats for treatment of flea infestations, and has also been experimented for use against the KS1 Ctenocephalides felis flea strain infesting dogs, in addition to many investigations for use in other animals and agricultural plants.
Indications and Usage Spinosad is indicated for the topical treatment of head lice in children four years old and over and in adults.
Marketing Status Prescription
ATC Code Not Available
DrugBank ID DB08823
KEGG ID D09384
MeSH ID C415329
PubChem ID 56841558
TTD Drug ID D09WCM
NDC Product Code 52246-929; 28595-570; 62158-0009; 62227-020
Synonyms spinosad
Chemical Information
Molecular Formula C83H132N2O20
CAS Registry Number 168316-95-8
SMILES CCC1CCCC(C(C(=O)C2=CC3C4CC(CC4C=CC3C2CC(=O)O1)OC5C(C(C(C(O5)C)OC)OC)OC)C)OC6CCC( C(O6)C)N(C)C.CCC1CCCC(C(C(=O)C2=CC3C4CC(CC4C(=CC3C2CC(=O)O1)C)OC5C(C(C(C(O5)C)OC )OC)OC)C)OC6CCC(C(O6)C)N(C)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Alopecia23.02.02.001--
Application site erythema23.03.06.005; 12.07.01.001; 08.02.01.001--Not Available
Application site irritation12.07.01.003; 08.02.01.003--Not Available
Dry skin23.03.03.001--
Erythema23.03.06.001--Not Available
Erythema of eyelid23.03.06.006; 06.04.04.003--Not Available
Application site dryness23.03.03.024; 12.07.01.011; 08.02.01.011--Not Available
Application site exfoliation12.07.01.022; 08.02.01.022; 23.03.07.007--Not Available
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