Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Sevelamer carbonate
Drug ID BADD_D02013
Description Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Indications and Usage For the control of serum phosphorus in patients with Chronic Kidney Disease (CKD) on hemodialysis.
Marketing Status Prescription; Discontinued
ATC Code V03AE02
DrugBank ID DB00658
KEGG ID D06642
MeSH ID D000069603
PubChem ID 11593706
TTD Drug ID D03MZQ
NDC Product Code 0955-1052; 16571-739; 65862-930; 65862-923; 17856-0921; 58468-0131; 70518-2490; 16714-814; 0955-1050; 55154-8188; 43826-139; 72643-013; 68382-824; 0904-6707; 60687-328; 65977-0078; 76339-144; 55111-789; 72969-101; 62147-0187; 0115-1366; 66499-0023; 50268-720; 65162-058; 70771-1520; 69452-126; 65015-748; 65862-931; 76282-664; 0115-1365; 69680-143; 65862-921; 58468-0132; 0955-1054; 71205-966; 0615-8239; 55154-3358; 69097-967; 69452-127; 58468-0130; 69097-893; 76282-407; 67787-407; 68094-034; 24979-186
Synonyms Sevelamer | GT335-012 | GT335 012 | GT335012 | Sevelamer Hydrochloride | Hydrochloride, Sevelamer | RenaGel | Sevelamer Carbonate | Carbonate, Sevelamer
Chemical Information
Molecular Formula C7H14ClNO4
CAS Registry Number 845273-93-0
SMILES C=CCN.C1C(O1)CCl.C(=O)(O)O
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Constipation07.02.02.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dyspepsia07.01.02.001--
Flatulence07.01.04.002--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Ileus07.13.01.001--
Intestinal obstruction07.13.01.002--Not Available
Intestinal perforation07.04.06.002--Not Available
Nausea07.01.07.001--
Peritonitis11.01.07.007; 07.19.05.004--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Vomiting07.01.07.003--
Subileus07.13.01.004--Not Available
Faecaloma07.01.03.004--Not Available
Faecalith07.01.03.007--Not Available
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