Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Sargramostim
Drug ID BADD_D01990
Description Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Indications and Usage For the treatment of cancer and bone marrow transplant
Marketing Status Prescription
ATC Code L03AA09
DrugBank ID DB00020
KEGG ID D05803
MeSH ID C081222
PubChem ID Not Available
TTD Drug ID D0XT5Y
NDC Product Code 71837-5843
Synonyms sargramostim | 23-L-leucine-colony-stimulating factor 2 (human clone pHG25 protein moiety) | Leukine | Prokine
Chemical Information
Molecular Formula Not Available
CAS Registry Number 123774-72-1
SMILES Not Available
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Alanine aminotransferase increased13.03.01.003--
Alopecia23.02.02.001--
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Blood albumin decreased13.09.01.001--Not Available
Blood calcium decreased13.11.01.002--Not Available
Blood cholesterol increased13.12.01.002--
Blood creatinine increased13.13.01.004--
Blood glucose increased13.02.02.002--Not Available
Blood urea increased13.13.01.006--Not Available
Bone pain15.02.01.001--
Cardiac arrest02.03.04.001--
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.001--
Coagulopathy01.01.02.001--Not Available
Constipation07.02.02.001--
Dermatitis allergic10.01.03.014; 23.03.04.003--Not Available
Diarrhoea07.02.01.001--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Dyspnoea22.02.01.004; 02.01.03.002--
Epistaxis22.04.03.001; 24.07.01.005--
Eye haemorrhage24.07.05.002; 06.07.02.001--Not Available
Gastric ulcer07.04.03.002--
Gastrointestinal disorder07.11.01.001--Not Available
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