| Pharmaceutical Information |
| Drug Name |
Rizatriptan benzoate |
| Drug ID |
BADD_D01958 |
| Description |
Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist. |
| Indications and Usage |
For treatment of acute migraine attacks with or without aura. |
| Marketing Status |
Prescription; Discontinued |
| ATC Code |
N02CC04 |
| DrugBank ID |
DB00953
|
| KEGG ID |
D00675
|
| MeSH ID |
C093622
|
| PubChem ID |
77997
|
| TTD Drug ID |
D0S9MU
|
| NDC Product Code |
51991-362; 64220-995; 70518-2957; 50090-3343; 50090-3921; 71335-1283; 63629-7433; 71335-0810; 43817-133; 68462-465; 29300-269; 71205-644; 70518-0509; 59746-415; 65862-625; 67877-262; 71335-1257; 57237-087; 51991-355; 68462-467; 69097-866; 63629-8256; 65862-626; 53747-043; 72189-258; 50090-4619; 65862-600; 43817-135; 69452-157; 71335-1172; 71335-1577; 69097-865; 51991-354; 65862-599; 72189-316; 55111-092; 78206-142; 71205-398; 0378-1403; 65372-1147; 69452-156; 55700-958; 67835-5016; 45865-825; 33342-093; 68462-468; 71335-1346; 57237-088; 53002-3713; 61919-656; 65015-653; 71205-557; 68462-466; 66039-835; 29300-268; 71335-1819; 67877-261; 51991-363; 59746-414; 64567-0013; 57237-085; 57237-086; 0093-7471; 53104-7580; 63187-563; 14593-872; 50090-3367; 72189-126; 29300-317; 33342-094; 0378-1404; 55700-942; 61919-394; 29300-316; 59746-446; 59746-445; 0093-7472; 78206-143; 71335-1912; 71335-1149; 64220-996; 53002-1713; 65862-578; 63629-8122; 71335-2031 |
| Synonyms |
rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt |
|
| Chemical Information |
| Molecular Formula |
C22H25N5O2 |
| CAS Registry Number |
145202-66-0 |
| SMILES |
CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3.C1=CC=C(C=C1)C(=O)O |
| Chemical Structure |
|
|
| ADR Related Proteins Induced by Drug |
| ADR Term |
Protein Name |
UniProt AC |
TTD Target ID |
PMID |
| Not Available | Not Available | Not Available | Not Available | Not Available |
|
| ADRs Induced by Drug |
|
| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
|
ADR Severity Grade (FAERS)
|
ADR Severity Grade (CTCAE)
|
| Hot flush | 24.03.01.005; 21.02.02.001; 08.01.03.027 | - | - | | | Ischaemia | 24.04.02.004 | - | - | Not Available | | Oropharyngeal pain | 22.02.05.022; 07.05.05.004 | - | - | |
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