Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rizatriptan
Drug ID BADD_D01957
Description Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Indications and Usage For treatment of acute migraine attacks with or without aura.
Marketing Status Prescription; Discontinued
ATC Code N02CC04
DrugBank ID DB00953
KEGG ID D08485
MeSH ID C093622
PubChem ID 5078
TTD Drug ID D0S9MU
NDC Product Code 63850-7138; 33342-087; 33342-088; 62938-0021; 62938-0022; 62938-0020; 63850-7119; 71335-1352; 62938-0019; 65977-0067
Synonyms rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt
Chemical Information
Molecular Formula C15H19N5
CAS Registry Number 144034-80-0
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cough22.02.03.001--
Cystitis20.03.02.002; 11.01.14.0010.000691%
Deafness04.02.01.001--Not Available
Dehydration14.05.05.001--
Depressed level of consciousness17.02.04.0020.001727%
Depressed mood19.15.02.0010.000691%Not Available
Depression19.15.01.0010.001727%
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Disorientation17.02.05.015; 19.13.01.002--Not Available
Disturbance in attention19.21.02.002; 17.03.03.001--
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
Drug abuse19.07.02.0100.000691%Not Available
Drug hypersensitivity10.01.01.0010.002764%Not Available
Dry eye06.08.02.001--
Dry mouth07.06.01.0020.000691%
Dry throat22.02.05.004; 07.06.01.005--Not Available
Dysaesthesia17.02.06.003--
Dysarthria19.19.03.001; 17.02.08.0010.001382%
Dysgeusia17.02.07.003; 07.14.03.0010.001036%
Dyspepsia07.01.02.001--
Dysphagia07.01.06.0030.000691%
Dysphonia22.02.05.005; 19.19.03.002; 17.02.08.004--
Dyspnoea22.02.01.004; 02.01.03.0020.002073%
Dysuria20.02.02.002--
Ear disorder04.03.01.001--Not Available
Ear pain04.03.01.003--
Electrocardiogram ST segment elevation13.14.05.0250.000691%Not Available
Epistaxis24.07.01.005; 22.04.03.001--
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